Peripheral inflammatory hyperalgesia is exacerbated in rats with metabolic disorders induced by a fructose diet

L Orlandi, MK Oliveira, F Vitor-Vieira… - Physiology …, 2024 - akjournals.com
This study explored the effects of fructose-induced obesity and metabolic disorders on
peripheral inflammatory hyperalgesia, employing quantitative sensory testing with the von …

High-fat diet causes mechanical allodynia in the absence of injury or diabetic pathology

JA Tierney, CD Uong, ME Lenert, M Williams… - Scientific reports, 2022 - nature.com
Understanding the interactions between diet, obesity, and diabetes is important to tease out
mechanisms in painful pathology. Western diet is rich in fats, producing high amounts of …

High-fat diet increases pain behaviors in rats with or without obesity

Z Song, W Xie, S Chen, JA Strong, MS Print, JI Wang… - Scientific reports, 2017 - nature.com
Obesity is associated with increased risk for chronic pain. Basic mechanisms for this
association are poorly understood. Using a milder version of a radicular pain model, local …

Fructose‐1,6‐bisphosphate reduces inflammatory pain‐like behaviour in mice: role of adenosine acting on A1 receptors

DA Valério, FI Ferreira, TM Cunha… - British journal of …, 2009 - Wiley Online Library
Background and purpose: D‐Fructose‐1, 6‐bisphosphate (FBP) is an intermediate in the
glycolytic pathway, exerting pharmacological actions on inflammation by inhibiting cytokine …

Acute intake of a high-fructose diet alters the balance of adipokine concentrations and induces neutrophil influx in the liver

DF Rodrigues, MC do Carmo Henriques… - The Journal of nutritional …, 2014 - Elsevier
The postprandial state is a period of metabolic fluxes, biosynthesis and oxidative
metabolism. A considerable amount is known about the inflammatory response to the …

Mechanisms of fructose-induced hypertension

TX Tran - 2009 - open.library.ubc.ca
The metabolic syndrome is a cluster of cardiovascular risk factors and is a global health
concern. The most accepted and unifying hypothesis proposes that insulin resistance is the …

Effects of soy diet on inflammation-induced primary and secondary hyperalgesia in rat

J Borzan, JM Tall, C Zhao, RA Meyer, SN Raja - European Journal of Pain, 2010 - Elsevier
Soy consumption is said to prevent or treat atherosclerosis, cancer, pain, and memory
deficits, but experimental and clinical evidence to support these claims are lacking. We used …

Fructose-induced insulin resistance as a model of neuropathic pain in rats

G García, EJ Gutiérrez-Lara, D Centurión… - Neuroscience, 2019 - Elsevier
Peripheral neuropathy is one of the main complications of diabetes. The pathogenesis of
this affectation is not completely understood. Several studies refer to hyperglycemia as the …

High fat diet sensitizes fibromyalgia-like pain behaviors in mice via tumor necrosis factor alpha

D Tian, M Tian, L Zhang, P Zhao, Y Cui, J Li - PloS one, 2018 - journals.plos.org
Fibromyalgia (FM) and obesity are closely related. However, little is known about how
obesity contributes to FM. Importantly, adequate evidence has shown that tumor necrosis …

Fructose induces visceral adipose tissue inflammation and insulin resistance even without development of obesity in adult female but not in male rats

S Kovačević, J Brkljačić, D Vojnović Milutinović… - Frontiers in …, 2021 - frontiersin.org
Introduction: Obesity and related metabolic disturbances are frequently related to modern
lifestyle and are characterized by excessive fructose intake. Visceral adipose tissue (VAT) …