Infectious Plasmodium sporozoites grown in vitro

AG Eappen, SL Hoffman - US Patent 11,883,475, 2024 - Google Patents
The application is directed to in vitro-reared Plasmodium sporozoites of human host range
wherein sporogony from gametocyte stage to sporozoite stage is external to mosquitoes …

Infectious plasmodium sporozoites grown in vitro

AG Eappen, SL Hoffman - US Patent 9,878,026, 2018 - Google Patents
The application is directed to in-vitro-reared Plasmodium sporozoites of human host range
wherein sporogony from gametocyte stage to sporozoite stage is external to mosquitoes …

Infectious plasmodium sporozoites grown in vitro

AG Eappen, SL Hoffman - US Patent 10,441,646, 2019 - Google Patents
The application is directed to in vitro-reared Plasmodium sporozoites of human host range
wherein sporogony from gametocyte stage to sporozoite stage is external to mosquitoes …

Infectious plasmodium sporozoites grown in vitro

AG Eappen, SL Hoffman - US Patent App. 18/532,731, 2024 - Google Patents
The application is directed to in vitro-reared Plasmodium sporozoites of human host range
wherein sporogony from gametocyte stage to sporozoite stage is external to mosquitoes …

Infectious plasmodium sporozoites grown in vitro

AG Eappen, SL Hoffman - US Patent 11,207,395, 2021 - Google Patents
The application is directed to in vitro-reared Plasmodium sporozoites of human host range
wherein sporogony from gametocyte stage to sporozoite stage is external to mosqui toes …

Method for developing malaria sporozoites in vitro

T Savransky, J Williams - US Patent 10,577,578, 2020 - Google Patents
US10577578B2 - Method for developing malaria sporozoites in vitro - Google Patents
US10577578B2 - Method for developing malaria sporozoites in vitro - Google Patents Method for …

Purified plasmodium and vaccine compositions

BKL Sim, M Li, RE Stafford, SL Hoffman - US Patent 10,272,146, 2019 - Google Patents
Disclosed are substantially purified Plasmodium sporozoites and preparations of
Plasmodium sporozoites substantially separated from attendant non-sporozoite material …

Purified Plasmodium and vaccine composition

BKL Sim, M Li, RE Stafford, SL Hoffman - US Patent 8,821,896, 2014 - Google Patents
Disclosed are substantially purified Plasmodium sporozoites and preparations of
Plasmodium sporozoites Substantially separated from attendant non-sporozoite material …

Purified Plasmodium and vaccine composition

BKL Sim, M Li, RE Stafford, SL Hoffman - US Patent 8,992,944, 2015 - Google Patents
Disclosed are substantially purified Plasmodium sporozoites and preparations of
Plasmodium sporozoites Substantially separated from attendant non-sporozoite material …

Apparatuses and methods for the production of haematophagous organisms and parasites suitable for vaccine production

SL Hoffman, TC Luke - US Patent 8,802,919, 2014 - Google Patents
Disclosed are apparatuses and methods for the production of attenuated aseptic parasites in
haematophagous insects generally, and production of Plasmodium species sporozoites in …