[HTML][HTML] Exposure to triphenyltin impairs gut integrity, disturbs gut microbiota, and alters fecal metabolites

X Chen, D Zhu, F Zhang, O Li, F Yang, Z Bao - … and Environmental Safety, 2024 - Elsevier
Triphenyltin is an environmental contaminant widely used in antifouling paints and can
cause toxicity in various organs in living organisms. However, its effects on intestinal …

[HTML][HTML] Fecal transplantation of young mouse donors effectively improves enterotoxicity in elderly recipients exposed to triphenyltin

X Chen, D Zhu, R Ge, Z Bao - Ecotoxicology and Environmental Safety, 2024 - Elsevier
Triphenyltin (TPT) is a widely used biocide known for its high toxicity to various organisms,
including humans, and its potential contribution to environmental pollution. The aging …

Gut microbiota-mediated tributyltin-induced metabolic disorder in rats

G Yuan, Z Zhang, X Gao, J Zhu, W Guo, L Wang… - RSC …, 2020 - pubs.rsc.org
Tributyltin (TBT), an environmental pollutant widely used in antifouling coatings, can cause
multiple-organ toxicity and gut microbiome dysbiosis in organisms, and can even cause …

Short-term triphenyltin exposure alters microbial homeostasis in the silkworm (Bombyx mori) midgut

W Zhou, X Zhang, X Chen, X Wu, A Ye, J Cao, X Hu - Scientific Reports, 2023 - nature.com
Triphenyltin (TPT) is a widespread synthetic chemical used in many fields and its potential
risk to organisms has been comprehensively investigated using different animal models and …

Tributyltin exposure induces gut microbiome dysbiosis with increased body weight gain and dyslipidemia in mice

H Guo, H Yan, D Cheng, X Wei, R Kou, J Si - Environmental toxicology and …, 2018 - Elsevier
Gut microbiome dysbiosis plays a profound role in the pathogenesis of obesity and tributyltin
(TBT) has been found as an environmental obesogen. However, whether TBT could disturb …

Triphenyltin exposure causes changes in health-associated gut microbiome and metabolites in marine medaka

S He, D Yu, P Li, M Zhang, S Xing, C Sun, ZH Li - Environmental Pollution, 2021 - Elsevier
Triphenyltin (TPT), an organic compound with a wide range of applications, is often detected
in water bodies and aquatic animals. However, the mechanism underlying the biological …

Gut microbiome alterations induced by tributyltin exposure are associated with increased body weight, impaired glucose and insulin homeostasis and endocrine …

J Zhan, X Ma, D Liu, Y Liang, P Li, J Cui, Z Zhou… - Environmental …, 2020 - Elsevier
Tributyltin (TBT), an organotin compound once widely used in agriculture and industry, has
been reported to induce obesity and endocrine disruption. Gut microbiota has a strong …

Transcriptomics-based analysis reveals the nephrotoxic effects of triphenyltin (TPT) on SD rats by affecting RAS, AQPs and lipid metabolism

M Qian, X Ren, P Mao, Z Li, T Qian, L Wang… - Pesticide Biochemistry …, 2024 - Elsevier
Triphenyltin (TPT) is a class of organotin compounds that are extensively used in industry
and agriculture. They have endocrine-disrupting effects and cause severe environmental …

[HTML][HTML] Effects of microplastics (MPs) and tributyltin (TBT) alone and in combination on bile acids and gut microbiota crosstalk in mice

P Jiang, G Yuan, B Jiang, J Zhang, Y Wang… - Ecotoxicology and …, 2021 - Elsevier
Microplastics (MPs) and tributyltin (TBT) are both potential environmental pollutants that
enter organisms through the food chain and affect bodily functions. However, the effects and …

Triphenyltin (TPT) exposure causes SD rat liver injury via lipid metabolism disorder and ER stress revealed by transcriptome analysis

X Ren, X Zhang, X Ma, H Liu, L Wang - Toxicology Letters, 2023 - Elsevier
Background TPT is an environmental endocrine disruptor that can interfere with endocrine
function. However, whether TPT can cause damage to liver structure and function and …