Abstract Three-dimensional (3D) in vitro neural tissue models provide a better recapitulation of in vivo cell-cell and cell-extracellular matrix interactions than conventional two …
AM Hopkins, E DeSimone, K Chwalek… - Progress in …, 2015 - Elsevier
There are currently more than 600 diseases characterized as affecting the central nervous system (CNS) which inflict neural damage. Unfortunately, few of these conditions have …
The brain is a complex 3-dimensional structure, the organization of which provides a local environment that directly influences the survival, proliferation, differentiation, migration, and …
Abstract Neurological disorders like Alzheimer, Huntington's, Epilepsy and conditions like traumatic brain injury often result in therapeutically intractable negative effects. The advent …
Advances in neural tissue engineering have resulted in the development and implementation of three-dimensional (3-D) neural cellular constructs, which may serve as …
M Köse-Dunn, R Fricker, P Roach - Adv Tissue Eng Regen Med Open …, 2017 - core.ac.uk
The increased prevalence of neurological diseases across the world has stimulated a great deal of research into the physiological and pathological brain, both at clinical and pre …
A Louit, T Galbraith, F Berthod - Bioengineering, 2023 - mdpi.com
The study of neurodegenerative diseases (such as Alzheimer's disease, Parkinson's disease, Huntington's disease, or amyotrophic lateral sclerosis) is very complex due to the …
C Traldi, V Chiappini, G Menduti… - Frontiers in Medical …, 2023 - frontiersin.org
Nowadays, the pathophysiology of several central nervous system (CNS) disorders is still poorly understood, making difficult the identification of efficient treatments. CNS damages …
F Rey, B Barzaghini, A Nardini, M Bordoni, GV Zuccotti… - Cells, 2020 - mdpi.com
In the field of regenerative medicine applied to neurodegenerative diseases, one of the most important challenges is the obtainment of innovative scaffolds aimed at improving the …