Advances in 3D tissue models for neural engineering: self-assembled versus engineered tissue models

S Wan, UA Robles, L Poole-Warren… - Biomaterials …, 2024 - pubs.rsc.org
Neural tissue engineering has emerged as a promising field that aims to create functional
neural tissue for therapeutic applications, drug screening, and disease modelling. It is …

3D neural tissue models: From spheroids to bioprinting

P Zhuang, AX Sun, J An, CK Chua, SY Chew - Biomaterials, 2018 - Elsevier
Abstract Three-dimensional (3D) in vitro neural tissue models provide a better recapitulation
of in vivo cell-cell and cell-extracellular matrix interactions than conventional two …

3D in vitro modeling of the central nervous system

AM Hopkins, E DeSimone, K Chwalek… - Progress in …, 2015 - Elsevier
There are currently more than 600 diseases characterized as affecting the central nervous
system (CNS) which inflict neural damage. Unfortunately, few of these conditions have …

Biomimetic materials and their utility in modeling the 3-dimensional neural environment

A Cembran, KF Bruggeman, RJ Williams, CL Parish… - Iscience, 2020 - cell.com
The brain is a complex 3-dimensional structure, the organization of which provides a local
environment that directly influences the survival, proliferation, differentiation, migration, and …

Self-organization in 3D neuronal constructs in vitro

MF Hasan - 2020 - search.proquest.com
Abstract Neurological disorders like Alzheimer, Huntington's, Epilepsy and conditions like
traumatic brain injury often result in therapeutically intractable negative effects. The advent …

Neural tissue engineering and biohybridized microsystems for neurobiological investigation in vitro (Part 1)

DK Cullen, JA Wolf, VN Vernekar… - Critical Reviews™ in …, 2011 - dl.begellhouse.com
Advances in neural tissue engineering have resulted in the development and
implementation of three-dimensional (3-D) neural cellular constructs, which may serve as …

[PDF][PDF] Tissue engineered organoids for neural network modelling

M Köse-Dunn, R Fricker, P Roach - Adv Tissue Eng Regen Med Open …, 2017 - core.ac.uk
The increased prevalence of neurological diseases across the world has stimulated a great
deal of research into the physiological and pathological brain, both at clinical and pre …

In vitro 3D modeling of neurodegenerative diseases

A Louit, T Galbraith, F Berthod - Bioengineering, 2023 - mdpi.com
The study of neurodegenerative diseases (such as Alzheimer's disease, Parkinson's
disease, Huntington's disease, or amyotrophic lateral sclerosis) is very complex due to the …

Advanced materials and biofabrication technologies to design in vitro functional central nervous system models

C Traldi, V Chiappini, G Menduti… - Frontiers in Medical …, 2023 - frontiersin.org
Nowadays, the pathophysiology of several central nervous system (CNS) disorders is still
poorly understood, making difficult the identification of efficient treatments. CNS damages …

Advances in tissue engineering and innovative fabrication techniques for 3-D-structures: translational applications in neurodegenerative diseases

F Rey, B Barzaghini, A Nardini, M Bordoni, GV Zuccotti… - Cells, 2020 - mdpi.com
In the field of regenerative medicine applied to neurodegenerative diseases, one of the most
important challenges is the obtainment of innovative scaffolds aimed at improving the …