Could Less Be More? Accounting for Fractional-Dose Regimens and Different Number of Vaccine Doses When Measuring the Impact of the RTS,S/AS01E Malaria …
N Westercamp, L Osei-Tutu… - The Journal of …, 2024 - academic.oup.com
Abstract Background The RTS, S/AS01E (RTS, S) malaria vaccine is recommended for
children in malaria endemic areas. This phase 2b trial evaluates RTS, S fractional-and full …
children in malaria endemic areas. This phase 2b trial evaluates RTS, S fractional-and full …
[HTML][HTML] Efficacy of RTS, S/AS01E malaria vaccine administered according to different full, fractional, and delayed third or early fourth dose regimens in children aged …
AM Samuels, D Ansong, SK Kariuki, S Adjei… - The Lancet Infectious …, 2022 - thelancet.com
Background Controlled infection studies in malaria-naive adults suggest increased vaccine
efficacy for fractional-dose versus full-dose regimens of RTS, S/AS01. We report first results …
efficacy for fractional-dose versus full-dose regimens of RTS, S/AS01. We report first results …
[HTML][HTML] Efficacy and safety of the RTS, S/AS01 malaria vaccine during 18 months after vaccination: a phase 3 randomized, controlled trial in children and young …
RTS, S Clinical Trials Partnership (2014) - PLoS medicine, 2014 - journals.plos.org
Background A malaria vaccine could be an important addition to current control strategies.
We report the safety and vaccine efficacy (VE) of the RTS, S/AS01 vaccine during 18 mo …
We report the safety and vaccine efficacy (VE) of the RTS, S/AS01 vaccine during 18 mo …
[HTML][HTML] Design of a phase III multicenter trial to evaluate the efficacy of the RTS, S/AS01 malaria vaccine in children across diverse transmission settings in Africa
A Leach, J Vekemans, M Lievens, O Ofori-Anyinam… - Malaria journal, 2011 - Springer
Abstract Background GlaxoSmithKline Biologicals and the PATH Malaria Vaccine Initiative
are working in partnership to develop a malaria vaccine to protect infants and children living …
are working in partnership to develop a malaria vaccine to protect infants and children living …
[HTML][HTML] Randomized Controlled Trial of RTS,S/AS02D and RTS,S/AS01E Malaria Candidate Vaccines Given According to Different Schedules in Ghanaian Children
S Owusu-Agyei, D Ansong, K Asante… - PLoS …, 2009 - journals.plos.org
Background The target delivery channel of RTS, S candidate malaria vaccines in malaria-
endemic countries in Africa is the World Health Organisation Expanded Program on …
endemic countries in Africa is the World Health Organisation Expanded Program on …
Efficacy and safety of RTS, S/AS01 malaria vaccine with or without a booster dose in infants and children in Africa: final results of a phase 3, individually randomised …
S Rts - Lancet, 2015 - thelancet.com
Background The efficacy and safety of the RTS, S/AS01 candidate malaria vaccine during
18 months of follow-up have been published previously. Herein, we report the final results …
18 months of follow-up have been published previously. Herein, we report the final results …
[HTML][HTML] Seven-year efficacy of RTS, S/AS01 malaria vaccine among young African children
Background The candidate malaria vaccine RTS, S/AS01 is being evaluated in order to
inform a decision regarding its inclusion in routine vaccination schedules. Methods We …
inform a decision regarding its inclusion in routine vaccination schedules. Methods We …
Feasibility, safety, and impact of the RTS, S/AS01E malaria vaccine when implemented through national immunisation programmes: evaluation of cluster-randomised …
Summary Background The RTS, S/AS01 E malaria vaccine (RTS, S) was introduced by
national immunisation programmes in Ghana, Kenya, and Malawi in 2019 in large-scale …
national immunisation programmes in Ghana, Kenya, and Malawi in 2019 in large-scale …
[HTML][HTML] RTS, S/AS01 malaria vaccine efficacy is not modified by seasonal precipitation: results from a phase 3 randomized controlled trial in Malawi
Abstract The World Health Organization has selected Malawi as one of three sites to pilot the
roll-out of RTS, S/AS01 in phase 4 trials. As policy discussions for the expanded use of RTS …
roll-out of RTS, S/AS01 in phase 4 trials. As policy discussions for the expanded use of RTS …
[HTML][HTML] First results of phase 3 trial of RTS, S/AS01 malaria vaccine in African children
RTS, S Clinical Trials Partnership - New England Journal of …, 2011 - Mass Medical Soc
Background An ongoing phase 3 study of the efficacy, safety, and immunogenicity of
candidate malaria vaccine RTS, S/AS01 is being conducted in seven African countries …
candidate malaria vaccine RTS, S/AS01 is being conducted in seven African countries …