The aging process has been one of the most necessary research fields in the current
century, and knowing different theories of aging and the role of different genetic, epigenetic …

Aging is the process of gradual physiological deterioration till death and this process
perpetually reduce the functionality of an individual. To address the rationale and provide …

Biological aging is characterized by irreversible cell cycle blockade, a decreased capacity
for tissue regeneration, and an increased risk of age-related diseases and mortality. A …

The aging phenotype is the result of a complex interaction between genetic, epigenetic and
environmental factors. Evidence suggests that epigenetic changes (ie, a set of reversible …

Epigenetics refers to phenotypic changes caused by mechanisms that are unrelated to
changes in the underlying DNA sequence, most notably chromatin remodeling driven by …

Aging represents the multifactorial decline in physiological function of every living organism.
Over the past decades, several hallmarks of aging have been defined, including epigenetic …

Aging is one of the most complex and irreversible health conditions characterized by
continuous decline in physical/mental activities that eventually poses an increased risk of …

It is tempting to assume that a gradual accumulation of damage 'causes 'an organism to age,
but other biological processes present during the lifespan, whether 'programmed 'or …

Aging is the largest risk factor for many diseases, and the aging population is one of the
fastest growing in the Western world. Therefore it has become ever more important to …

A global DNA hypomethylation and local changes in the methylation levels of specific DNA
loci occur during aging in mammals. Global hypomethylation mainly affects highly …