Growing evidence supports the suggestion that the peripheral immune system plays a role
in different pathologies associated with cognitive impairment, such as vascular dementia …

Knowledge regarding putative inflammatory component (s) participating in Alzheimer's
disease (AD) and in vascular dementia (VAD) remains scarce. Recently, we have …

Alzheimer's disease (AD) is a neurodegenerative disorder marked by progressive
impairment of cognitive ability. Patients with AD display neuropathological lesions including …

Alzheimer's disease (AD) is associated with a significant neuroinflammatory component.
Mononuclear phagocytes including monocytes and microglia are the principal cells …

Alzheimer's disease (AD) is a chronic neurodegenerative disorder and the main cause of
dementia. The disease is among the leading medical concerns of the modern world …

Cerebral amyloid angiopathy (CAA) is a critical factor in the pathogenesis of Alzheimer's
disease (AD). In the clinical setting, nearly 98% AD patients have CAA, and 75% of these …

Alzheimer's disease (AD) is a complex degenerative disorder of the brain, associated with a
progressive cognitive decline. Age is the main risk factor with almost half of the population …

Alzheimer's disease (AD) is the leading cause of dementia in the United States. Sporadic or
late-onset AD remains incompletely understood, with age as the current greatest risk factor …

For decades, several axioms have prevailed with respect to the relationships between the
CNS and circulating immune cells. Specifically, immune cell entry was largely considered to …

Alzheimer's disease (AD) is a serious brain disorder characterized by the presence of beta-
amyloid plaques, tau pathology, inflammation, neurodegeneration, and cerebrovascular …