Quantification of vaccine waning as a challenge effect
M Janvin, MJ Stensrud - arXiv preprint arXiv:2405.01336, 2024 - arxiv.org
Knowing whether vaccine protection wanes over time is important for health policy and drug
development. However, quantifying waning effects is difficult. A simple contrast of vaccine …
development. However, quantifying waning effects is difficult. A simple contrast of vaccine …
Reliably assessing duration of protection for COVID-19 vaccines
Decision-making about booster dosing for COVID-19 vaccine recipients hinges on reliable
methods for evaluating the longevity of vaccine protection. We show that modeling of …
methods for evaluating the longevity of vaccine protection. We show that modeling of …
Reliably assessing duration of protection for coronavirus disease 2019 vaccines
Decision making about vaccination and boosting schedules for coronavirus disease 2019
(COVID-19) hinges on reliable methods for evaluating the longevity of vaccine protection …
(COVID-19) hinges on reliable methods for evaluating the longevity of vaccine protection …
[HTML][HTML] Assessing durability of vaccine effect following blinded crossover in COVID-19 vaccine efficacy trials
Background: Several candidate vaccines to prevent COVID-19 disease have entered large-
scale phase 3 placebo-controlled randomized clinical trials and some have demonstrated …
scale phase 3 placebo-controlled randomized clinical trials and some have demonstrated …
Discussion on “estimating vaccine efficacy over time after a randomized study is unblinded” by Anastasios A. Tsiatis and Marie Davidian
D Follmann - Biometrics, 2022 - academic.oup.com
Evaluation of COVID-19 vaccines has proceeded at unprecedented speed and required the
quick development of statistical methods to emerging challenges in design and analysis. A …
quick development of statistical methods to emerging challenges in design and analysis. A …
A log-odds system for waning and boosting of COVID-19 vaccine effectiveness
Immunity to SARS-CoV-2 following vaccination wanes over time in a non-linear fashion,
making modelling of likely population impacts of COVID-19 policy options challenging. We …
making modelling of likely population impacts of COVID-19 policy options challenging. We …
Rejoinder: Estimating vaccine efficacy over time after a randomized study is unblinded
AA Tsiatis, M Davidian - Biometrics, 2022 - academic.oup.com
We are honored to have our work critiqued by such distinguished, internationally recognized
authorities on vaccine efficacy and vaccine trials. When the first author (AAT) was appointed …
authorities on vaccine efficacy and vaccine trials. When the first author (AAT) was appointed …
Discussion on “Estimating vaccine efficacy over time after a randomized study is unblinded” by Anastasios A. Tsiatis and Marie Davidian
A recent publication by Tsiatis and Davidian addresses the challenge of evaluating longer
term efficacy of a COVID-19 vaccine in the context of a blinded, placebo-controlled phase 3 …
term efficacy of a COVID-19 vaccine in the context of a blinded, placebo-controlled phase 3 …
Immunological heterogeneity informs estimation of the durability of vaccine protection
M Domenech de Cellès, A Wong… - Journal of the …, 2022 - royalsocietypublishing.org
Deciphering the properties of vaccines against an emerging pathogen is essential for
optimizing immunization strategies. Early after vaccine roll-out, however, uncertainties about …
optimizing immunization strategies. Early after vaccine roll-out, however, uncertainties about …
[图书][B] Could Vaccine Dose Stretching Reduce COVID-19 Deaths?
June 2021 Abstract: We argue that alternative COVID-19 vaccine dosing regimens could
potentially dramatically accelerate global COVID-19 vaccination and reduce mortality, and …
potentially dramatically accelerate global COVID-19 vaccination and reduce mortality, and …