Formic acid (HCOOH) and dihydrogen (H 2) are characteristic products of enterobacterial
mixed-acid fermentation, with H 2 generation increasing in conjunction with a decrease in …

Enterobacteria such as Escherichia coli generate formate, lactate, acetate, and succinate as
major acidic fermentation products. Accumulation of these products in the cytoplasm would …

During enterobacterial mixed-acid fermentation, formate is generated from pyruvate by the
glycyl-radical enzyme pyruvate formate-lyase (PflB). In Escherichia coli, especially at low …

Pentameric FocA permeates either formate or formic acid bidirectionally across the
cytoplasmic membrane of anaerobically growing Escherichia coli. Each protomer of FocA …

Formate is the signature compound in the anaerobic metabolism of Escherichia coli and
other enterobacteria. Its synthesis and degradation is integrated in a net-work of metabolic …

The production of dihydrogen by Escherichia coli and other members of the
Enterobacteriaceae is one of the classic features of mixed-acid fermentation. Synthesis of …

Escherichia coli encodes two formate channels, FocA and FocB, that either export formate or
import it for further disproportionation by the formate hydrogenlyase (FHL) complex to H2 …

Abstract Formate hydrogenlyase-1 (FHL-1) is a complex-I-like enzyme that is commonly
found in gram-negative bacteria. The enzyme comprises a peripheral arm and a membrane …

Abstract Escherichia coli FocA and FocB formate channels export formate or import it for
further disproportionation by the formate hydrogenlyase (FHL) complex to H 2 and CO 2 …

Fermentative hydrogen production by enterobacteria derives from the activity of the formate
hydrogenlyase (FHL) complex, which couples formate oxidation to H2 production. The …