Chromatin accessibility remodeling driven by pioneer factors is critical for the development
of early embryos. Current studies have illustrated several pioneer factors as being important …

Chromatin reorganization governs the regulation of gene expression during preimplantation
development. However, the landscape of chromatin dynamics in this period has not been …

The post‐transfer developmental capacity of bovine somatic cell nuclear transfer (SCNT)
blastocysts is reduced, implying that abnormalities in gene expression regulation are …

The study of chromatin accessibility across tissues and developmental stages is essential for
elucidating the transcriptional regulation of various phenotypes and biological processes …

Background Early post-implantation development, especially gastrulation in primates, is
accompanied by extensive drastic chromatin reorganization, which remains largely elusive …

Abstract K (lysine) acetyltransferase 8 (KAT8), an acetyltransferase that specifically
catalyzes histone H4 lysine 16 acetylation, is critical for key biological processes including …

Background Given their physiological similarities to humans, pigs are increasingly used as
model organisms in human-oriented biomedical studies. Additionally, their value to animal …

Upon fertilization, extensive chromatin reprogramming occurs during preimplantation
development. Growing evidence reveals species-dependent regulations of this process in …

How the chromatin regulatory landscape in the inner cell mass cells is established from
differentially packaged sperm and egg genomes during preimplantation development is …

Background Pigs are important animals for agricultural and biomedical research, and
improvement is needed for use of the assisted reproductive technologies. Determining …