Parkinson's disease (PD) is a common neurodegenerative disease, and apart from a few
rare genetic causes, its pathogenesis remains largely unclear. Recent scientific interest has …

Background: Iron is important in the pathophysiology of Parkinson's disease (PD)
specifically related to degeneration of the substantia nigra (SN). Magnetic resonance …

Brain-iron deposition has been proposed to play an important role in the pathophysiology of
Parkinson's disease (PD). The aim of this study was to evaluate the feasibility of …

Background Elevated brain iron has been observed in Idiopathic Parkinson's disease (IPD)
within the deep gray matter. Using quantitative susceptibility mapping (QSM) and a …

In Parkinson's disease (PD), iron elevation in specific brain regions as well as selective loss
of dopaminergic neurons is a major pathologic feature. A reliable quantitative measure of …

Background Iron deposition within the substantia nigra (SN) has been postulated to play a
vital role in Parkinson's disease (PD). The aim of this study was to explore the inherent link …

Abstract Background and Purpose Excessive brain iron deposition is involved in Parkinson's
disease (PD) pathogenesis. However, the correlation of iron accumulation in various brain …

Iron deposition in the brain normally increase with age, but its accumulation in certain
regions is observed in a number of neurodegenerative diseases including Parkinson's …

The identification of sensitive and specific biomarkers for Parkinson's disease (PD) poses an
important clinical challenge. A potential biomarker for early diagnosis and disease …

Background: Parkinson's disease (PD) is a progressive neurodegenerative disease whose
main neuropathological feature is the loss of dopaminergic neurons of the substantia nigra …