Healthy blood, healthy brain: a window into understanding and treating neurodegenerative diseases

TR Cardim-Pires, A de Rus Jacquet, F Cicchetti - Journal of Neurology, 2024 - Springer
Our limited understanding of complex neurodegenerative disorders has held us back on the
development of efficient therapies. While several approaches are currently being …

Blood-based therapies to combat neurodegenerative diseases

JY Lee, MCX Lim, RY Koh, MT Tsen, SM Chye - Metabolic Brain Disease, 2024 - Springer
Neurodegeneration, known as the progressive loss of neurons in terms of their structure and
function, is the principal pathophysiological change found in the majority of brain-related …

Young blood products: emerging treatment for Alzheimer's disease?

R Khoury, E Ghossoub - Neural regeneration research, 2018 - journals.lww.com
Alzheimer's disease is the most common neurodegenerative disorder and no disease-
modifying treatment is currently available. Research has shown that while brain …

Blood-borne revitalization of the aged brain

JM Castellano, ED Kirby, T Wyss-Coray - JAMA neurology, 2015 - jamanetwork.com
In the modern medical era, more diverse and effective treatment options have translated to
increased life expectancy. With this increased life span comes increased age-associated …

Rejuvenating the blood and bone marrow to slow aging-associated cognitive decline and Alzheimer's disease

S Kang, VA Moser, CN Svendsen… - Communications …, 2020 - nature.com
Parabiosis, blood exchange and plasma transfer experiments have highlighted the
rejuvenating properties of young blood. Our Communications Biology study demonstrated …

[HTML][HTML] Therapeutic potential of systemic brain rejuvenation strategies for neurodegenerative disease

AM Horowitz, SA Villeda - F1000Research, 2017 - ncbi.nlm.nih.gov
Neurodegenerative diseases are a devastating group of conditions that cause progressive
loss of neuronal integrity, affecting cognitive and motor functioning in an ever-increasing …

Blood-based therapies to combat aging

JM Castellano - Gerontology, 2019 - karger.com
Dysfunction associated with the aging process positions aging as a leading culprit for
development of devastating diseases and mounting health-care costs. Many age-associated …

Neuroscience: The power of plasma

L Drew - Nature, 2017 - nature.com
Neuroscience: The power of plasma | Nature Skip to main content Thank you for visiting
nature.com. You are using a browser version with limited support for CSS. To obtain the best …

Young blood plasma administration to fight Alzheimer's disease?

G Aicardi - Rejuvenation Research, 2018 - liebertpub.com
Despite decades of intensive research, no drugs can cure or even stabilize Alzheimer's
disease (AD). Current pharmacological treatments only partially mask the symptoms while …

Preclinical assessment of young blood plasma for Alzheimer disease

J Middeldorp, B Lehallier, SA Villeda… - JAMA …, 2016 - jamanetwork.com
Importance Alzheimer disease (AD) pathology starts long before clinical symptoms manifest,
and there is no therapy to treat, delay, or prevent the disease. A shared blood circulation …