More than ever, scientific progress in cancer research hinges on our ability to combine
datasets and extract meaningful interpretations to better understand diseases and ultimately …

Advancements in next-generation sequencing and other-omics technologies are
accelerating the detailed molecular characterization of individual patient tumors, and driving …

Abstract The NCI Cancer Research Data Commons (CRDC) is a collection of data
commons, analysis platforms, and tools that make existing cancer data more findable and …

Abstract The NCI's Cloud Resources (CR) are the analytical components of the Cancer
Research Data Commons (CRDC) ecosystem. This review describes how the three CRs …

Since 2014, the NCI has launched a series of data commons as part of the Cancer Research
Data Commons (CRDC) ecosystem housing genomic, proteomic, imaging, and clinical data …

Abstract The National Cancer Institute (NCI) Cancer Research Data Commons (CRDC) aims
to establish a national cloud-based data science infrastructure. Imaging Data Commons …

Background With the development of cancer precision medicine, a huge amount of high-
dimensional cancer information has rapidly accumulated regarding gene alterations …

Abstract The NCI Genomic Data Commons (GDC) was launched in 2016 and makes
available over 4 petabytes (PB) of cancer genomic and associated clinical data to the …

The analysis of big healthcare data has enormous potential as a tool for advancing oncology
drug development and patient treatment, particularly in the context of precision medicine …

One of the recommendations of the Cancer Moonshot Blue Ribbon Panel report from 2016
was the creation of a national cancer data ecosystem. We review some of the approaches …