Inflammation: A key process in skin tumorigenesis

M Neagu, C Constantin, C Caruntu… - Oncology …, 2019 - spandidos-publications.com
The extremely delicate shift from an inflammatory process to tumorigenesis is a field of major
scientific interest. While the inflammation induced by environmental agents has well known …

Galectins and galectin-mediated autophagy regulation: new insights into targeted cancer therapy

D Liu, H Zhu, C Li - Biomarker Research, 2023 - Springer
Galectins are animal lectins with specific affinity for galactosides via the conserved
carbohydrate recognition domains. Increasing studies recently have identified critical roles …

Matricellular proteins in cutaneous wound healing

CG Cárdenas-León, K Mäemets-Allas… - Frontiers in Cell and …, 2022 - frontiersin.org
Cutaneous wound healing is a complex process that encompasses alterations in all aspects
of the skin including the extracellular matrix (ECM). ECM consist of large structural proteins …

Galectins and ovarian cancer

C Shimada, R Xu, L Al-Alem, M Stasenko, DR Spriggs… - Cancers, 2020 - mdpi.com
Ovarian cancer is known for its aggressive pathological features, including the capacity to
undergo epithelial to mesenchymal transition, promoting angiogenesis, metastatic potential …

Expression pattern and immunoregulatory roles of Galectin-1 and Galectin-3 in atopic dermatitis and psoriasis

MP Corrêa, RD Correia-Silva, GRS Sasso… - Inflammation, 2022 - Springer
The pathogenesis of atopic dermatitis (AD) and psoriasis (Ps) overlaps, particularly the
activation of the immune response and tissue damage. Here, we evaluated galectin (Gal)-1 …

Evaluation of Plasma Concentrations of Galectins-1, 2 and 12 in Psoriasis and Their Clinical Implications

J Nowowiejska, A Baran, JM Hermanowicz… - Biomolecules, 2023 - mdpi.com
Psoriasis is a complex disease that nowadays is considered not only a dermatosis but a kind
of systemic disorder associated with many accompanying diseases. Metabolic complications …

Unraveling how tumor-derived galectins contribute to anti-cancer immunity failure

DJ Laderach, D Compagno - Cancers, 2021 - mdpi.com
Simple Summary This review compiles our current knowledge of one of the main pathways
activated by tumors to escape immune attack. Indeed, it integrates the current understanding …

Galectin-1 and galectin-3 and their potential binding partners in the dermal thickening of keloid tissues

E Arciniegas, LM Carrillo, H Rojas… - The American Journal …, 2019 - journals.lww.com
Keloids are defined histopathologically as an inflammatory disorder characterized by
exhibiting numerous fibroblasts, abnormal vascularization, increased number of …

[HTML][HTML] Galectins for diagnosis and prognostic assessment of human diseases: an overview of meta-analyses

Y Liu, H Meng, S Xu, X Qi - Medical Science Monitor: International …, 2020 - ncbi.nlm.nih.gov
An increasing number of studies have explored the activities and functions of galectins.
However, translation of these researches into clinical practice seems to be lacking. As …

Galectin-3 regulates UVB-induced inflammation in skin

JY Wang, PH Lu, WW Lin, YH Wei, LY Chiu… - Journal of …, 2020 - Elsevier
Background Galectin-3 is widely expressed in many immunocytes and epithelial cells
including skin keratinocytes. Galectin-3 can regulate immunological or inflammatory …