The core protein of the hepatitis C virus is derived from the N-terminal 191 amino acids of
the viral polyprotein by proteolytic cleavage. In the current study, subcellular localizations of …

To begin a successful infection, viruses must first cross the host cell plasma membrane,
either by direct fusion with the membrane or by receptor-mediated endocytosis. After release …

Abstract Canine parvovirus 2 (CPV-2) is a well-recognized cause of acute haemorrhagic
enteritis in dogs worldwide. The aim of the current study was to identify which CPV-2 …

Antibody binding and neutralization are major host defenses against viruses, yet the
mechanisms are often not well understood. Eight monoclonal antibodies and their Fab …

Abstract Background Canine parvovirus 2 (CPV 2) is a major infectious cause of mortality in
puppies. The characteristic symptom of CPV 2 disease is intestinal hemorrhage with severe …

The VP2 structural protein of parvovirus can produce virus-like particles (VLPs) by a self-
assembly process in vitro, making VLPs attractive vaccine candidates. In this study, the VP2 …

Capsids of autonomous parvoviruses are assembled from two proteins, VP1 and VP2, which
overlap in sequence, with VP1 having additional amino-terminal residues. Empty capsids …

The degree of genetic heterogeneity of DNA virus populations in nature and its
consequences for disease control are virtually unknown. The parvovirus minute virus of mice …

Animal viruses have developed various strategies for infecting cells, and all begin with
adsorption to cell surface receptors, penetration into the cytosol, uncoating or release of the …

Parvovirus capsids are small but complex molecular machines responsible for undertaking
many of the steps of cell infection, genome packing, and cell-to-cell as well as host-to-host …