Therapeutic potential and pharmacological significance of extracellular vesicles derived from traditional medicinal plants

P Wu, W Wu, S Zhang, J Han, C Liu, H Yu… - Frontiers in …, 2023 - frontiersin.org
Medicinal plants are the primary sources for the discovery of novel medicines and the basis
of ethnopharmacological research. While existing studies mainly focus on the chemical …

Plant-derived vesicle-like nanoparticles: A new tool for inflammatory bowel disease and colitis-associated cancer treatment

X Fang, J Feng, X Zhu, D Feng, L Zheng - Molecular Therapy, 2024 - cell.com
Long-term use of conventional drugs to treat inflammatory bowel diseases (IBD) and colitis-
associated cancer (CAC) has an adverse impact on the human immune system and easily …

Tomato-fruit-derived extracellular vesicles inhibit Fusobacterium nucleatum via lipid-mediated mechanism

BH Lee, SC Wu, HY Chien, TL Shen, WH Hsu - Food & function, 2023 - pubs.rsc.org
Nano-sized extracellular vesicles (EV) are essential for cell communication. Studies on EV
from natural sources including edible plants are gaining momentum due to the biological …

[HTML][HTML] Bioactive compounds and biological functions of medicinal plant-derived extracellular vesicles

S Hao, H Yang, J Hu, L Luo, Y Yuan, L Liu - Pharmacological Research, 2024 - Elsevier
Extracellular vesicles (EVs) are tiny lipid bilayer-enclosed membrane particles released from
a variety of cell types into the surrounding environment. These EVs have massive …

Isolation and Characterization of Extracellular Vesicles from Arabidopsis thaliana Cell Culture and Investigation of the Specificities of Their Biogenesis

Y Yugay, Z Tsydeneshieva, T Rusapetova… - Plants, 2023 - mdpi.com
Over recent years, extracellular vesicles (EVs), commonly termed exosomes, have gained
prominence for their potential as natural nanocarriers. It has now been recognized that …

Edible plant-derived extracellular vesicles for oral mRNA vaccine delivery

C Gai, MAC Pomatto, MC Deregibus, M Dieci, A Piga… - Vaccines, 2024 - mdpi.com
Nucleic acid delivery through extracellular vesicles (EVs) is a well-preserved evolutionary
mechanism in all life kingdoms including eukaryotes, prokaryotes, and plants. EVs naturally …

Microbial assistance in nano-carrier development: Innovative strategies in drug delivery

T Pandey, V Pandey - Journal of Drug Delivery Science and Technology, 2024 - Elsevier
Microbial-assisted synthesis has emerged as a promising avenue in the field of drug
delivery, offering innovative solutions to overcome challenges associated with traditional …

[HTML][HTML] Food-derived vesicles as immunomodulatory drivers: Current knowledge, gaps, and perspectives

F Rivero-Pino, E Marquez-Paradas… - Food Chemistry, 2024 - Elsevier
Extracellular vesicles (EVs) are lipid-bound membrane vesicles released from cells,
containing active compounds, which can be found in different foods. In this review, the role …

The Discovery of Extracellular Vesicles and Their Emergence as a Next-Generation Therapy

A Rai, B Claridge, J Lozano, DW Greening - Circulation Research, 2024 - Am Heart Assoc
From their humble discovery as cellular debris to cementing their natural capacity to transfer
functional molecules between cells, the long-winded journey of extracellular vesicles (EVs) …

Extracellular vesicles for developing targeted hearing loss therapy

X Pan, Y Li, P Huang, H Staecker, M He - Journal of Controlled Release, 2024 - Elsevier
Substantial efforts have been made for local administration of small molecules or biologics
in treating hearing loss diseases caused by either trauma, genetic mutations, or drug …