Long-term and sequential treatment for osteoporosis

I Foessl, HP Dimai, B Obermayer-Pietsch - Nature Reviews …, 2023 - nature.com
Osteoporosis is a skeletal disorder that causes impairment of bone structure and strength,
leading to a progressively increased risk of fragility fractures. The global prevalence of …

[HTML][HTML] The RANK/RANKL/OPG system and tumor bone metastasis: Potential mechanisms and therapeutic strategies

Y Zhang, J Liang, P Liu, Q Wang, L Liu… - Frontiers in …, 2022 - frontiersin.org
With the markedly increased diagnosis and incidence of cancer in the population, tumor
bone metastasis has become a frequent event in tumor patients. Healthy bone integrity is …

[HTML][HTML] Bone-derived PDGF-BB drives brain vascular calcification in male mice

J Wang, CL Fang, K Noller, Z Wei, G Liu… - The Journal of …, 2023 - Am Soc Clin Investig
Brain vascular calcification is a prevalent age-related condition often accompanying
neurodegenerative and neuroinflammatory diseases. The pathogenesis of large-vessel …

Nanoscale interactions of humic acid and minerals reveal mechanisms of carbon protection in soil

M Yu, Y Hua, MT Sarwar, H Yang - Environmental Science & …, 2022 - ACS Publications
The concentrations of terrestrially sourced dissolved organic matter (DOM) have expanded
throughout aquatic ecosystems in recent decades. Although sorption to minerals in soils is …

A seminal perspective on the role of chondroitin sulfate in biomineralization

J Hao, Q Wan, Z Mu, J Gu, W Yu, W Qin, Y Li… - Carbohydrate …, 2023 - Elsevier
Chondroitin sulfate (CS) is an important extracellular matrix component of mineralized
tissues. It participates in biomineralization, osteoblast differentiation and promotes bone …

[HTML][HTML] Osteomalacia is not a single disease

L Cianferotti - International Journal of Molecular Sciences, 2022 - mdpi.com
Among bone-material qualities, mineralization is pivotal in conferring stiffness and
toughness to the bone. Osteomalacia, a disease ensuing from inadequate mineralization of …

Biomimetic mineralization by confined diffusion with viscous hyaluronan network: Assembly of hierarchical flower-like supraparticles

X Ma, L Ma, Y Tan, X Chen, Q Tong, L Tang, X Cao… - Carbohydrate …, 2023 - Elsevier
Biomolecules-mediated biomimetic mineralization has been extensively investigated and
applied to fabricate nano-assemblies with unique hierarchical architectures and salient …

[HTML][HTML] Osteomalacia in adults: A practical insight for clinicians

L Arboleya, I Braña, E Pardo, M Loredo… - Journal of Clinical …, 2023 - mdpi.com
The term osteomalacia (OM) refers to a series of processes characterized by altered
mineralization of the skeleton, which can be caused by various disorders of mineral …

[HTML][HTML] X-linked hypophosphatemia caused by a deep intronic variant in PHEX identified by PCR-based RNA analysis of urine-derived cells

C Grimbly, K Ludwig, Z Wu, O Caluseriu, E Rosolowsky… - Bone, 2023 - Elsevier
X-linked hypophosphatemia (XLH) is caused by dominant inactivating mutations in the
phosphate regulating endopeptidase homology, X-linked (PHEX), resulting in elevated …

[HTML][HTML] Nano-Topographically Guided, Biomineralized, 3D-Printed Polycaprolactone Scaffolds with Urine-Derived Stem Cells for Promoting Bone Regeneration

F Xing, HY Shen, M Zhe, K Jiang, J Lei, Z Xiang, M Liu… - Pharmaceutics, 2024 - mdpi.com
Currently, biomineralization is widely used as a surface modification approach to obtain
ideal material surfaces with complex hierarchical nanostructures, morphologies, unique …