In the realm of biomedical engineering and materials science, the synthesis of biomaterials
plays a pivotal role in advancing therapeutic strategies for regeneration of tissues. The …

Conventional biomineralization strategies are constructed using microparticles, suffering the
inhibition of protease bio-availability and required rigorous bio-evaluation. The use of …

Skeletal fluorosis likely alters bone structural properties on the cortical and cancellous tissue
levels in view that fluorine ion replaces bone mineral composition. Our previous study …

GATM-related Fanconi renotubular syndrome 1 (FRTS1) is a form of renal Fanconi
syndrome (RFS), which is a disorder of solute and water reabsorption caused by defects in …

Autosomal recessive hypophosphatemic rickets type 2 (ARHR2; MIM# 613312) is a very
rare disorder caused by biallelic loss-of-function mutations in the ENPP1 (ectonucleotide …

目的· 构建并验证可模拟维生素A 缺乏症(vitamin A deficiency, VAD) 导致的颅颌面骨畸形且
出生后可存活的模型小鼠. 方法· 运用Cre-LoxP 重组酶系统, 通过将Osx Cre 与Rosa26 …

Substantial progress has been made in defining genes and proteins involved in the
development, maintenance and regeneration of teeth and bones. This knowledge has …

Cranial sutures are complex structures integrating mechanical forces with osteogenesis
which are often affected in craniofacial syndromes. While premature fusion is frequently …

Background and aims The role of aortic mineralization in the pathogenesis of acute type B
aortic dissection (TBAD) is unclear. Whether thoracic aortic calcification (TAC) and …

Solid state nuclear magnetic resonance (SSNMR), a technique capable of studying solid or
semisolid biological samples, was first applied to study the cell differentiation and …