Perimenopause is an important stage of female senescence. Epidemiological investigation
has shown that the incidence of cardiovascular disease in premenopausal women is lower …

Cardiovascular disease (CVD) is the leading cause of morbidity and mortality worldwide.
There is robust evidence of heterogeneity in underlying mechanism, manifestation …

Background The early life environment experienced by an individual in utero and during the
neonatal period is a major factor in shaping later life disease risk-including susceptibility to …

Obesity increases the risks of developing cardiovascular and metabolic diseases and
degrades quality of life, ultimately increasing the risk of death. However, not all forms of …

Gender-affirming or cross-sex hormone therapy is integral to the management of
transgender individuals yet our appreciation of the effects of such hormones on …

Osteoporosis, a metabolic bone disease characterized by low bone mineral density and
deterioration of bone microarchitecture, has led to a high risk of fatal osteoporotic fractures …

Background Dietary risks have raised attention worldwide during recent decades. The
present burden‐of‐disease study aimed to evaluate the global dietary risks for non …

Cardiovascular disease remains the leading cause of death in women. Given accumulating
evidence on sex-and gender-based differences in cardiovascular disease development and …

Nonalcoholic fatty liver disease (NAFLD) embraces the clinico-pathological consequences
of hepatic lipotoxicity and is a major public health problem globally. Sexual dimorphism is a …

Brown adipose tissue (BAT) activity contributes to cardiovascular health by its energy-
dissipating capacity but how BAT modulates vascular function and atherosclerosis through …