[HTML][HTML] PTH and vitamin D

SJ Khundmiri, RD Murray, E Lederer - Comprehensive Physiology, 2016 - ncbi.nlm.nih.gov
PTH and Vitamin D are two major regulators of mineral metabolism. They play critical roles
in the maintenance of calcium and phosphate homeostasis as well as the development and …

Physiology and pathophysiology of the intrarenal renin-angiotensin system: an update

T Yang, C Xu - Journal of the American Society of Nephrology, 2017 - journals.lww.com
The renin-angiotensin system (RAS) has a pivotal role in the maintenance of extracellular
volume homeostasis and blood pressure through complex mechanisms. Apart from the well …

Nuclear receptors in podocyte biology and glomerular disease

S Agrawal, JC He, PL Tharaux - Nature Reviews Nephrology, 2021 - nature.com
Nuclear receptors have a broad spectrum of biological functions in normal physiology and in
the pathology of various diseases, including glomerular disease. The primary therapies for …

The emerging role of vitamin D and vitamin D receptor in diabetic nephropathy

M Lei, Z Liu, J Guo - BioMed research international, 2020 - Wiley Online Library
Diabetic nephropathy (DN), one of the most common and severe microvascular
complications of diabetes mellitus (DM), is an important risk factor for DM patient's death …

Efficacy of high-dose supplementation with oral vitamin D3 on depressive symptoms in dialysis patients with vitamin D3 insufficiency: a prospective, randomized …

Y Wang, Y Liu, Y Lian, N Li, H Liu… - Journal of clinical …, 2016 - journals.lww.com
Psychological problems are common among end-stage renal disease patients undergoing
dialysis. We aim to evaluate whether high-dose vitamin D3 (VD3) supplementation has …

Vitamin D levels decline with rising number of cardiometabolic risk factors in healthy adults: association with adipokines, inflammation, oxidative stress and advanced …

Z Krivošíková, M Gajdoš, K Šebeková - PLoS One, 2015 - journals.plos.org
Introduction Hypovitaminosis D associates with obesity, insulin resistance, hypertension,
and dyslipoproteinemia. We asked whether the presence of multiple cardiometabolic risk …

The kidney-heart connection in obesity

A García-Carrasco, A Izquierdo-Lahuerta… - Nephron, 2021 - karger.com
There is a strong relationship between the kidney and the heart, where if one of these
organs fails, so does the other, in the so-called cardiorenal syndrome (CRS). Besides, there …

Hepatocyte gene expression and DNA methylation as ancestry-dependent mechanisms in African Americans

CS Park, T De, Y Xu, Y Zhong, E Smithberger… - NPJ Genomic …, 2019 - nature.com
Abstract African Americans (AAs) are an admixed population with widely varying proportion
of West African ancestry (WAA). Here we report the correlation of WAA to gene expression …

Co-targeting of endothelin-A and vitamin D receptors: a novel strategy to ameliorate cisplatin-induced nephrotoxicity

LMA Moneim, MW Helmy, HS El-Abhar - Pharmacological Reports, 2019 - Elsevier
Background Although modulation of the vitamin D receptor (VDR) and endothelin-A receptor
(ET AR) has previously been reported to offer renoprotection against cisplatin-induced …

Vitamin D and diabetes mellitus

AM Urbanovych, SI Shykula - International Journal of …, 2022 - iej.zaslavsky.com.ua
Vitamin D is a very important prohormone that needs for maintaining homeostasis and
harmonious work of the endocrine system. This review article shows the impact of vitamin D …