Multifunctional nanoparticle-mediated combining therapy for human diseases

X Li, X Peng, M Zoulikha, GF Boafo, KT Magar… - … and Targeted Therapy, 2024 - nature.com
Combining existing drug therapy is essential in developing new therapeutic agents in
disease prevention and treatment. In preclinical investigations, combined effect of certain …

[HTML][HTML] Current research trends of nanomedicines

Q Liu, J Zou, Z Chen, W He, W Wu - Acta Pharmaceutica Sinica B, 2023 - Elsevier
Owing to the inherent shortcomings of traditional therapeutic drugs in terms of inadequate
therapeutic efficacy and toxicity in clinical treatment, nanomedicine designs have received …

[HTML][HTML] Lipid carriers for mRNA delivery

W Zhang, Y Jiang, Y He, H Boucetta, J Wu… - … Pharmaceutica Sinica B, 2023 - Elsevier
Messenger RNA (mRNA) is the template for protein biosynthesis and is emerging as an
essential active molecule to combat various diseases, including viral infection and cancer …

Hydrogel-mediated drug delivery for treating stroke

W Yu, E Gong, B Liu, L Zhou, C Che, S Hu… - Chinese Chemical …, 2023 - Elsevier
Stroke is a common disease and is the major cause of death and disability. It occurs and
generates devastating neurological deficits when cerebral blood vessel is blocked (ischemic …

CAR-T cells for cancer immunotherapy

Y Xie, X Li, J Wu, H Zeng, H Boucetta, B Wang… - Chinese Chemical …, 2023 - Elsevier
Adoptive immunotherapy expressing synthetic chimeric antigen receptors (CAR) on T cells
through in vitro modifications represents a new and innovative strategy in cancer treatment …

Diclofenac, ibuprofen, and paracetamol biodegradation: overconsumed non-steroidal anti-inflammatories drugs at COVID-19 pandemic

BL Ferreira, DP Ferreira, SF Borges… - Frontiers in …, 2023 - frontiersin.org
The consumption of non-steroidal anti-inflammatory drugs (NSAIDs) have increased
significantly in the last years (2020–2022), especially for patients in COVID-19 treatment …

In silico identification of potential miRNAs-mRNA inflammatory networks implicated in the pathogenesis of COVID-19

SH Sheikhshabani, Z Amini-Farsani, P Modarres… - Human Gene, 2023 - Elsevier
COVID-19 has been found to affect the expression profile of several mRNAs and miRNAs,
leading to dysregulation of a number of signaling pathways, particularly those related to …

The interaction between particles and vascular endothelium in blood flow

X Li, J Zou, Z He, Y Sun, X Song, W He - Advanced Drug Delivery Reviews, 2024 - Elsevier
Particle-based drug delivery systems have shown promising application potential to treat
human diseases; however, an incomplete understanding of their interactions with vascular …

Low-dose radiation therapy (LDRT) against cancer and inflammatory or degenerative diseases: Three parallel stories with a common molecular mechanism involving …

E Le Reun, N Foray - Cancers, 2023 - mdpi.com
Simple Summary We reviewed the medical applications of low-dose radiation therapy
(LDRT) in cancer and inflammatory and degenerative diseases by proposing a unified …

COVID‐19 and primary wound healing: A new insights and advance

D Li, W Cao, Q Zhou, X Wu, X Song… - International Wound …, 2023 - Wiley Online Library
With the outbreak and pandemic of coronavirus disease‐2019 (COVID‐19), a huge number
of people died of it. Apart from lung injuries, multiple organs have been confirmed to be …