Single-cell immunology of SARS-CoV-2 infection

Y Tian, LN Carpp, HER Miller, M Zager… - Nature …, 2022 - nature.com
Gaining a better understanding of the immune cell subsets and molecular factors associated
with protective or pathological immunity against severe acute respiratory syndrome …

Guidance for the management of patients with vascular disease or cardiovascular risk factors and COVID-19: position paper from VAS-European independent …

GT Gerotziafas, M Catalano, MP Colgan… - Thrombosis and …, 2020 - thieme-connect.com
COVID-19 is also manifested with hypercoagulability, pulmonary intravascular coagulation,
microangiopathy, and venous thromboembolism (VTE) or arterial thrombosis. Predisposing …

[HTML][HTML] A new hope? Possibilities of therapeutic IgA antibodies in the treatment of inflammatory lung diseases

F Bohländer - Frontiers in Immunology, 2023 - frontiersin.org
Inflammatory lung diseases represent a persistent burden for patients and the global
healthcare system. The combination of high morbidity,(partially) high mortality and limited …

Reynoutria Rhizomes as a Natural Source of SARS-CoV-2 Mpro Inhibitors–Molecular Docking and In Vitro Study

I Nawrot-Hadzik, M Zmudzinski, A Matkowski… - Pharmaceuticals, 2021 - mdpi.com
More than a year has passed since the world began to fight the novel severe acute
respiratory syndrome coronavirus 2 (SARS-CoV-2) responsible for the Coronavirus disease …

Peptide-based vaccines and therapeutics for COVID-19

PV Bagwe, PV Bagwe, SS Ponugoti… - International Journal of …, 2022 - Springer
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has been prevalent in the
humans since 2019 and has given rise to a pandemic situation. With the discovery and …

From anti-SARS-CoV-2 immune response to the cytokine storm via molecular mimicry

D Kanduc - Antibodies, 2021 - mdpi.com
The aim of this study was to investigate the role of molecular mimicry in the cytokine storms
associated with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Human …

Outcomes of patients with severe and critical COVID-19 treated with dexamethasone: a prospective cohort study

BA Martinez-Guerra, MF Gonzalez-Lara… - Emerging Microbes & …, 2022 - Taylor & Francis
Dexamethasone implementation for COVID-19 management represented a milestone but
data regarding its impact and safety have not been consistently reproduced. We aimed to …

Immunomodulation and regenerative capacity of MSCs for long-COVID

XY Loke, SAM Imran, GJ Tye… - International Journal of …, 2021 - mdpi.com
The rapid mutation of the SARS-CoV-2 virus is now a major concern with no effective drugs
and treatments. The severity of the disease is linked to the induction of a cytokine storm that …

Molecular insights into the MAPK cascade during viral infection: potential crosstalk between HCQ and HCQ analogues

TK Mohanta, N Sharma, P Arina… - BioMed Research …, 2020 - Wiley Online Library
The mitogen‐activated protein kinase (MAPK) pathway links the cell‐surface receptors to the
transcription machinery, transducing the extracellular signals into several outputs, which …

Dexmedetomidine alleviates acute lung injury by promoting Tregs differentiation via activation of AMPK/SIRT1 pathway

Z Zhang, K Xie, R Luo, D Zhang, Z He, K Li, S Lin… - …, 2023 - Springer
Objectives To explore the anti-inflammatory effect and the potential mechanism of
dexmedetomidine in ARDS/ALI. Materials and Methods C57BL/6 mice and EL-4 cells were …