Background The amount of publicly available cancer-related “omics” data is constantly
growing and can potentially be used to gain insights into the tumour biology of new cancer …

Malignant melanoma is widely acknowledged as the most lethal skin malignancy. The
metabolic reprogramming in melanoma leads to alterations in glycolysis and oxidative …

Cervical squamous cell carcinoma (CSCC) is the major pathological type of cervical cancer
(CC), the second most prevalent reproductive system malignant tumor threatening the health …

Although laboratory studies have implicated the high mobility group box 1 (HMGB1) in
melanoma, its clinical relevance remains unclear. We analyzed nearly 100 cases of human …

Melanoma is an aggressive type of cancer originating from the skin that arises from
neoplastic changes in melanocytes. Transforming growth factor‑β (TGF‑β) is a pleiotropic …

Several reports have demonstrated a role for aberrant NOTCH signaling in melanoma
genesis and progression, prompting us to explore if targeting this pathway is a valid …

There is ample evidence that the presence of tumor-infiltrating T lymphocytes is associated
with a favorable prognostic in patients. These observations suggest that a limiting step to …

Earlier identification of aggressive melanoma remains a goal in the field of melanoma
research. With new targeted and immune therapies that have revolutionized the care of …

In the recent decade, cutting edge molecular and proteomic analysis platforms
revolutionized biomarkers discovery in cancers. Melanoma is the prototype with over 51,100 …

Background and aim Nucleolar and spindle-associated protein 1 (NUSAP1) is an
indispensable mitotic regulator. Aberrant NUSAP1 expression is associated with perturbed …