[HTML][HTML] Thermal titration molecular dynamics (TTMD): shedding light on the stability of RNA-small molecule complexes
Ribonucleic acids are gradually becoming relevant players among putative drug targets,
thanks to the increasing amount of structural data exploitable for the rational design of …
thanks to the increasing amount of structural data exploitable for the rational design of …
SARS-CoV-2 nsp15 preferentially degrades AU-rich dsRNA via its dsRNA nickase activity
X Wang, B Zhu - Nucleic Acids Research, 2024 - academic.oup.com
It has been proposed that coronavirus nsp15 mediates evasion of host cell double-stranded
(ds) RNA sensors via its uracil-specific endoribonuclease activity. However, how nsp15 …
(ds) RNA sensors via its uracil-specific endoribonuclease activity. However, how nsp15 …
[HTML][HTML] Applications of Molecular Docking Studies in SARS-CoV-2 Targeted Drug Discovery and the Gains Achieved through Molecular Docking
M Yildirim, I Celik - 2024 - intechopen.com
In this chapter, we delve into the pivotal role of molecular docking in the realm of
computational biology and chemistry, focusing specifically on its application in drug …
computational biology and chemistry, focusing specifically on its application in drug …
A functional medicine and food homology composition discovery based on disease-related target and data mining against cardiac remodeling
D Xiao, R Li, X Qin, J Feng, D Baranenko, L Natdochii… - bioRxiv, 2024 - biorxiv.org
Background: Medicine and food homological (MFH) products exhibit enhanced safety and
tolerability, minimizing notable side effects, making them pivotal for prolonged use in …
tolerability, minimizing notable side effects, making them pivotal for prolonged use in …
In Silico Insights Toward the Exploration of Adenosine Receptors Ligand Recognition
Adenosine receptors have been studied for many years now, their structures have been
resolved and many of the determinants for their interaction patterns have been highlighted …
resolved and many of the determinants for their interaction patterns have been highlighted …
[HTML][HTML] Potential protective effects of Huanglian Jiedu Decoction against COVID-19-associated acute kidney injury: A network-based pharmacological and molecular …
W Wu, Y Zhang, G Liu, Z Chi, A Zhang, S Miao… - Open …, 2023 - degruyter.com
Abstract Corona virus disease 2019 (COVID-19) is prone to induce multiple organ damage.
The kidney is one of the target organs of SARS-CoV-2, which is susceptible to inducing …
The kidney is one of the target organs of SARS-CoV-2, which is susceptible to inducing …
[HTML][HTML] ¿ Cómo podemos encontrar la mejor ruta de recolección de basura?
OM Cano, MAP Blas, PV Saravia - Revista Digital Universitaria, 2024 - revista.unam.mx
Enfrentando el desafío de optimizar la recolección de basura en la colonia Rosarito, Los
Cabos, México, utilizamos herramientas de la Teoría de Gráficas para modelar y resolver el …
Cabos, México, utilizamos herramientas de la Teoría de Gráficas para modelar y resolver el …
[HTML][HTML] ¿ Es posible identificar nuevos fármacos desde tu computadora?
MTA Parra, MGM Montelongo… - Revista Digital …, 2024 - revista.unam.mx
Resumen¿ Cómo se obtienen los nuevos fármacos?¿ De dónde salen nuevos productos
para descontaminar un lago o el suelo? Las plantas y los microorganismos producen …
para descontaminar un lago o el suelo? Las plantas y los microorganismos producen …