Comparative analysis of SARS-CoV-2 neutralization titers reveals consistency between human and animal model serum and across assays

B Mühlemann, SH Wilks, L Baracco, M Bekliz… - Science Translational …, 2024 - science.org
The evolution of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) requires
ongoing monitoring to judge the ability of newly arising variants to escape the immune …

Pseudoviruses, a safer toolbox for vaccine development against enveloped viruses

SR Thimmiraju, JT Kimata, J Pollet - Expert Review of Vaccines, 2024 - Taylor & Francis
Introduction Pseudoviruses are recombinant, replication-incompetent, viral particles
designed to mimic the surface characteristics of native enveloped viruses. They are a safer …

[HTML][HTML] Full-spike deep mutational scanning helps predict the evolutionary success of SARS-CoV-2 clades

B Dadonaite, J Brown, TE McMahon, AG Farrell… - biorxiv, 2023 - ncbi.nlm.nih.gov
SARS-CoV-2 variants acquire mutations in spike that promote immune evasion and impact
other properties that contribute to viral fitness such as ACE2 receptor binding and cell entry …

A pan-influenza monoclonal antibody neutralizes H5 strains and prophylactically protects through intranasal administration

AL Beukenhorst, J Frallicciardi, KL Rice, MH Koldijk… - Scientific Reports, 2024 - nature.com
Abstract Avian A (H5N1) influenza virus poses an elevated zoonotic threat to humans, and
no pharmacological products are currently registered for fast-acting pre-exposure protection …

Double-blinded, randomised, placebo-controlled trial of convalescent plasma for COVID-19: analyses by neutralising antibodies homologous to recipients' variants

T Khawaja, M Kajova, I Levonen, JP Pietilä… - Infectious …, 2024 - Taylor & Francis
Introduction Convalescent plasma (CP) emerged as potential treatment for COVID-19 early
in the pandemic. While efficacy in hospitalised patients has been lacklustre, CP may be …

An Evaluation of a SARS-CoV-2 Pseudovirus Neutralization Test and A Comparison to a SARS-CoV-2 Surrogate Virus Neutralization Test in a COVID-19 Long-Term …

C Gillot, J Favresse, C David, V Maloteau… - Microbiology …, 2024 - mdpi.com
Background: The detection of neutralizing anti-SARS-CoV-2 antibodies is important since
they represent the subset of antibodies able to prevent the virus to invade human cells. The …

[HTML][HTML] Deep mutational scanning reveals functional constraints and antigenic variability of Lassa virus glycoprotein complex

CR Carr, KHD Crawford, M Murphy, JG Galloway… - bioRxiv, 2024 - ncbi.nlm.nih.gov
Lassa virus is estimated to cause thousands of human deaths per year, primarily due to
spillovers from its natural host, Mastomys rodents. Efforts to create vaccines and antibody …

Safety and immunogenicity of heterologous boosting with a bivalent SARS-CoV-2 mRNA vaccine (XBB. 1.5/BQ. 1) in Chinese participants aged 18 years or more: A …

YW Su, YZ Qiu, YH Wang, Y Xu, CC Huang, Q Zhang… - Vaccine, 2024 - Elsevier
Continuous emergence of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)
variants urges the development of new vaccines. We assessed the safety and …

Comparative analysis of serological assays and sero-surveillance for SARS-CoV-2 exposure in US cattle

S Ramasamy, M Qureshi, S Mukherjee, S Mahajan… - bioRxiv, 2024 - biorxiv.org
Coronavirus disease-2019 (COVID-19) caused by severe acute respiratory syndrome
coronavirus-2 (SARS-CoV-2) continues to pose a significant threat to public health globally …

Serological analysis in humans in Malaysian Borneo suggests prior exposure to H5 avian influenza

H Klim, T William, C Brady, T Chua, HB Monzó… - 2024 - researchsquare.com
Cases of H5 highly pathogenic avian influenzas (HPAI) are on the rise. Although
mammalian spillover events are rare, H5N1 viruses have an estimated mortality rate in …