Objectives: To provide guidance for the management of mood disorders, based on scientific
evidence supplemented by expert clinical consensus and formulate recommendations to …

An estimated 50% of depressed patients are inadequately treated by available interventions.
Even with an eventual recovery, many patients require a trial and error approach, as there …

We propose that depression can be viewed as an adaptation to conserve energy after the
perceived loss of an investment in a vital resource such as a relationship, group identity, or …

With growing recognition that bullying is a complex phenomenon, influenced by multiple
factors, research findings to date have been understood within a social-ecological …

Background Burnout among physicians affects mental health, performance, and patient
outcomes. Surgery residency is a high-risk time for burnout. We examined burnout and the …

Whether burnout is a form of depression or a distinct phenomenon is an object of
controversy. The aim of the present article was to provide an up-to-date review of the …

In this paper, we characterize major depression (MD) as a complex dynamic system in which
symptoms (eg, insomnia and fatigue) are directly connected to one another in a network …

Background Results from longitudinal studies on sleep duration and incidence of
depression remain controversial. Methods PubMed and Web of Science updated on October …

Major depressive disorder (MDD) is a common, debilitating, phenotypically heterogeneous
disorder with heritability ranges from 30% to 50%. Compared to other psychiatric disorders …

The goal of the present protocol is to describe the forced swim test (FST), which is one of the
most commonly used assays for the study of depressive-like behavior in rodents. The FST is …