Some individuals with a particular disease-causing mutation or genotype fail to express most if not all features of the disease in question, a phenomenon that is known as 'reduced …
Major Depressive Disorder Working Group of … - Molecular …, 2013 - ncbi.nlm.nih.gov
Prior genome-wide association studies (GWAS) of major depressive disorder (MDD) have met with limited success. We sought to increase statistical power to detect disease loci by …
MC Keller - Biological psychiatry, 2014 - Elsevier
Candidate gene× environment (G× E) interaction research tests the hypothesis that the effects of some environmental variable (eg, childhood maltreatment) on some outcome …
Mental toughness (MT) is an umbrella term that entails positive psychological resources, which are crucial across a wide range of achievement contexts and in the domain of mental …
Early life stress, such as childhood abuse, neglect and loss, is a well established major risk factor for developing depressive disorders later in life. We here summarize and discuss …
Drawing on state-of-the-art personality and developmental research, this book presents a new and broadly integrative theory of how people come to be who they are over the life …
How do our brains determine whether something is good or bad? How is this computational goal implemented in biological systems? Given the critical importance of valence processing …
AL Byers, K Yaffe - Nature Reviews Neurology, 2011 - nature.com
Depression is highly common throughout the life course and dementia is common in late life. Depression has been linked with dementia, and growing evidence implies that the timing of …
Ambulatory assessment (AA) covers a wide range of assessment methods to study people in their natural environment, including self-report, observational, and biological/physiological …