Proteomics profiling of microdissected low-and high-grade prostate tumors identifies Lamin A as a discriminatory biomarker
S Skvortsov, G Schäfer, T Stasyk… - Journal of proteome …, 2011 - ACS Publications
Proteomics screening methods for the identification of diagnostic and prognostic biomarkers
in cancer are still lagging behind DNA-or RNA-based analysis. We used two-dimensional …
in cancer are still lagging behind DNA-or RNA-based analysis. We used two-dimensional …
miR-128 and miR-149 enhance the chemosensitivity of temozolomide by Rap1B-mediated cytoskeletal remodeling in glioblastoma
X She, Z Yu, Y Cui, Q Lei, Z Wang, G Xu… - Oncology …, 2014 - spandidos-publications.com
Glioblastoma multiforme (GBM) is one of the most deadly diseases affecting humans, and is
often characterized by poor survival and by high resistance to chemotherapy and …
often characterized by poor survival and by high resistance to chemotherapy and …
miR-128 exerts pro-apoptotic effect in a p53 transcription-dependent and-independent manner via PUMA-Bak axis
YK Adlakha, N Saini - Cell death & disease, 2013 - nature.com
Abstract p53 has attracted tremendous attention due to its master role in tumor development.
Activation of p53 in tumor cells has been the prime focus for cancer drug discovery. Recent …
Activation of p53 in tumor cells has been the prime focus for cancer drug discovery. Recent …
Eight‐plex iTRAQ analysis of variant metastatic human prostate cancer cells identifies candidate biomarkers of progression: an exploratory study
BACKGROUND Due to the heterogeneity in the biological behavior of prostate cancer,
biomarkers that can reliably distinguish indolent from aggressive disease are urgently …
biomarkers that can reliably distinguish indolent from aggressive disease are urgently …
The Role of miR-128 in Neurodegenerative Diseases
Several neurodegenerative disorders are characterized by the accumulation of misfolded
proteins and are collectively known as proteinopathies. Alzheimer's disease (AD) …
proteins and are collectively known as proteinopathies. Alzheimer's disease (AD) …
Metabolomic profiling identifies biochemical pathways associated with castration-resistant prostate cancer
AK Kaushik, SK Vareed, S Basu, V Putluri… - Journal of proteome …, 2014 - ACS Publications
Despite recent developments in treatment strategies, castration-resistant prostate cancer
(CRPC) is still the second leading cause of cancer-associated mortality among American …
(CRPC) is still the second leading cause of cancer-associated mortality among American …
Evaluation and prognostic significance of ACAT1 as a marker of prostate cancer progression
INTRODUCTION Prostate cancer is the second leading cause of cancer‐related death
among men in North America. While a majority of prostate cancer cases remain indolent …
among men in North America. While a majority of prostate cancer cases remain indolent …
Temporally altered miRNA expression in a piglet model of hypoxic ischemic brain injury
Hypoxic ischemic encephalopathy (HIE) is the most frequent cause of acquired infant brain
injury. Early, clinically relevant biomarkers are required to allow timely application of …
injury. Early, clinically relevant biomarkers are required to allow timely application of …
The role of miRNA-128 in the development and progression of gastrointestinal and urogenital cancer
Increasing data have shown the significance of various miRNAs in malignancy. In this
regard, parallel to its biological role in normal tissues, miRNA-128 (miR-128) has been …
regard, parallel to its biological role in normal tissues, miRNA-128 (miR-128) has been …
miRNAs as biomarkers in prostate cancer
I Casanova-Salas, J Rubio-Briones… - Clinical and …, 2012 - Springer
Current prostate cancer (PCa) diagnosis is based in the serum prostate-specific antigen
biomarker and digital rectal examination. However, these methods are limited by a low …
biomarker and digital rectal examination. However, these methods are limited by a low …