This study aimed to investigate more detailed functions of circ_0005276 in prostate cancer
(PCa) and provide a novel mechanism for circ_0005276 action. The expression of …

Inflammasomes are cytoplasmic receptors that can recognize intracellular pathogens or
danger signals and are critical for interleukin 1β production. Although several key …

Numerous efforts have been made to indentify reliable and predictive biomarkers to detect
the early signs of smoking-induced lung disease. Using 6-month cigarette smoking in mice …

To date, there is still shortage of highly sensitive and specific minimally invasive biomarkers
for assessment of environmental toxicants exposure. Because of the significance of …

MicroRNAs (miRNAs) are noncoding RNAs that control gene expression either by
degradation of mRNAs or inhibition of protein translation. miR-148a has been reported to …

Current therapies for prostate cancer include antiandrogens, inhibitory ligands of the
androgen receptor, which repress androgen-stimulated growth. These include the selective …

Mitochondrial dysfunction and vesicular trafficking alterations have been implicated in the
pathogenesis of several neurodegenerative diseases. It has become clear that pathogenetic …

Pancreatic Adenocarcinoma (PDAC), the fourth highest cause of cancer related deaths in
the United States, has the most aggressive presentation resulting in a very short median …

Objective: To investigate the regulatory function of exosome-transmitted miR-128 and
chemokine (CC motif) ligand 18 (CCL18) on urothelial carcinomas (UCs). Methods: Tumor …

miR-128 has been associated with cancer, particularly with leukemia. In particular, this miR
has been described, together with other miRs, to allow the discrimination between AML …