RNA m6A modification in prostate cancer: A new weapon for its diagnosis and therapy

Z Han, X Yi, J Li, T Zhang, D Liao, J You, J Ai - Biochimica et Biophysica …, 2023 - Elsevier
Prostate cancer (PCa) is the most common malignant tumor and the second leading cause
of cancer-related mortality in men worldwide. Despite significant advances in PCa therapy …

[HTML][HTML] Exploring the role of the inflammasomes on prostate cancer: Interplay with obesity

JM Pérez-Gómez, AJ Montero-Hidalgo… - Reviews in Endocrine …, 2023 - Springer
Obesity is a weight-related disorder characterized by excessive adipose tissue growth and
dysfunction which leads to the onset of a systemic chronic low-grade inflammatory state …

Crosstalk between m6A RNA methylation and miRNA biogenesis in cancer: An unholy nexus

PJ Jayasree, S Dutta, P Karemore, P Khandelia - Molecular Biotechnology, 2023 - Springer
Abstract N6-methyladenosine (m6A) is one of the most prevalent internal reversible
chemical modification of RNAs in eukaryotes, which has attracted widespread attention …

Recent advances in the reciprocal regulation of m6A modification with non-coding RNAs and its therapeutic application in acute myeloid leukemia

J Yang, F Liang, F Zhang, H Zhao, Q Gong… - Pharmacology & …, 2024 - Elsevier
Abstract N 6-methyladenosine (m 6 A) is one of the most common modifications of RNA in
eukaryotic cells and is involved in mRNA metabolism, including stability, translation …

[HTML][HTML] Non-coding RNA-Mediated N6-Methyladenosine (m6A) deposition: A pivotal regulator of cancer, impacting key signaling pathways in carcinogenesis and …

M Hashemi, P Daneii, MA Zandieh, R Raesi… - Non-coding RNA …, 2023 - Elsevier
The emergence of RNA modifications has recently been considered as critical post-
transcriptional regulations which governed gene expression. N 6-methyladenosine (m 6 A) …

[HTML][HTML] What should be the future direction of development in the field of prostate cancer with lung metastasis?

ZG Huang, Y Chen, T Wu, BT Yin, X Feng… - World Journal of …, 2023 - ncbi.nlm.nih.gov
BACKGROUND Since the start of the 21 st century, prostate cancer with lung metastasis
(PCLM) has accumulated significant scientific research output. However, a systematic …

[HTML][HTML] Demethylases in tumors and the tumor microenvironment: Key modifiers of N6-methyladenosine methylation

J Guo, L Zhao, M Duan, Z Yang, H Zhao, B Liu… - Biomedicine & …, 2024 - Elsevier
RNA methylation modifications are widespread in eukaryotes and prokaryotes, with N 6-
methyladenosine (m 6 A) the most common among them. Demethylases, including Fat mass …

[HTML][HTML] Role of N6‑methyladenosine in the pathogenesis, diagnosis and treatment of prostate cancer

J Pan, F Tong, N Ren, L Ren, Y Yang… - Oncology …, 2024 - spandidos-publications.com
Prostate cancer (PCa) affects males of all racial and ethnic groups, and leads to higher rates
of mortality in those belonging to a lower socioeconomic status due to the late detection of …

Fat mass and obesity-associated protein (FTO)-induced upregulation of flotillin-2 (FLOT2) contributes to cancer aggressiveness in diffuse large B-cell lymphoma …

Y Zhang, Y Chen, Q Guo, Y Zhang, A Liu - Archives of Biochemistry and …, 2024 - Elsevier
The role of fat mass and obesity-associated protein (FTO)-mediated N6-methyladenosine
(m6A)-demethylation has been investigated in various types of cancers, but it is still unclear …

[HTML][HTML] Integrated analysis of the potential roles of microRNA-messenger RNA networks in prostate adenocarcinoma

N Zhang, J Jin, X Ye - Heliyon, 2023 - cell.com
Background Prostate adenocarcinoma is a frequent cancer among men with high incidence
and mortality rates. Biomarkers are useful for the treatment of cancers, so we need to …