The endothelium is considered to be the gatekeeper of the vessel wall, maintaining and
regulating vascular integrity. In patients with chronic kidney disease, protective endothelial …

Background: Endothelium is the inner cellular lining of the vessels that modulates multiple
biological processes including vasomotor tone, permeability, inflammatory responses …

Rationale & Objective Previous studies in chronic kidney disease (CKD) showed that
vascular dysfunction in different circulatory beds progressively deteriorates with worsening …

Patients with chronic kidney disease (CKD) have an increased risk for cardiovascular
morbidity and mortality. Capillary rarefaction may be both one of the causes as well as a …

This study aimed to investigate whether Chronic Kidney Disease (CKD) influences O 2
supply including O 2 delivery and release to the active muscles during maximal physical …

Background Cognitive impairment and exercise intolerance are common in chronic kidney
disease (CKD). Cerebral perfusion and oxygenation play a major role in both cognitive …

Introduction: Cardiovascular disease is a major cause of death in chronic obstructive
pulmonary disease (COPD), but the relationship between these two entities is not fully …

Aim The burden of several cardiovascular risk factors increases in parallel to renal function
decline. Exercise intolerance is common in patients with chronic kidney disease (CKD) and …

Microvascular dysfunction is one of the hallmarks of systemic sclerosis (SSc). The presence
of pulmonary-arterial-hypertension (PAH) in SSc-patients is associated with poor prognosis …

Background Cardiovascular disease is the major cause of morbidity and mortality in patients
with chronic kidney disease (CKD). Endothelial dysfunction, the hallmark of atherosclerosis …