The ovary is a female reproductive organ that plays a key role in fertility and the
maintenance of endocrine homeostasis, which is of great importance to women's health. It is …

With the development of single‐cell RNA sequencing technology (scRNA‐seq), we have the
ability to study biological questions at the level of the individual cell transcriptome …

Domestication and artificial selection during production-oriented breeding have greatly
shaped the level of genomic variability in sheep. However, the genetic variation associated …

The pelviperineal organs of the female reproductive tract form an essential cornerstone of
human procreation. The system comprises the ectodermal external genitalia, the Müllerian …

The molecular mechanisms controlling the transition from meiotic arrest to meiotic
resumption in mammalian oocytes have not been fully elucidated. Single-cell omics …

Background In the modern sheep production systems, the reproductive performance of ewes
determines the economic profitability of farming. Revealing the genetic mechanisms …

The majority of activated ovarian follicles undergo atresia during reproductive life in
mammals, and only a small number of follicles are ovulated. Though hormone treatment has …

Background The ovaries are one of the first organs that undergo degenerative changes
earlier in the aging process, and ovarian aging is shown by a decrease in the number and …

In 2004, the identification of female germline or oogonial stem cells (OSCs) that can support
post–natal oogenesis in ovaries of adult mice sparked a major paradigm shift in reproductive …

The activation, growth, and maturation of oocytes to an ovulatory phase, termed
folliculogenesis, is governed by the orchestrated activity of multiple specialized cell types …