An Update on the Nitrogen Heterocycle Compositions and Properties of US FDA-Approved Pharmaceuticals (2013–2023)

CM Marshall, JG Federice, CN Bell… - Journal of Medicinal …, 2024 - ACS Publications
This Perspective is a continuation of our analysis of US FDA-approved small-molecule drugs
(1938–2012) containing nitrogen heterocycles. In this study we report drug structure and …

A review of thin films used in smart contact lenses

M Kareem, T Agbaje, F Alam… - Advanced Engineering …, 2024 - Wiley Online Library
Smart contact lenses incorporate a diversity of thin‐film components and are also fabricated
utilizing different thin films. They have been developed for the sensing and treatment of …

Slug-flow microextraction mass spectrometry for enhanced detection of analytes in human tear fluids using noninvasive microsampling and nanoelectrospray …

S Dong, N Zhang, M Yi, J Zhang, D Di, J Deng… - Analytical …, 2023 - ACS Publications
In vivo noninvasive sampling and sensitive analysis of human tear fluids at the microliter
level is an important but challenging task in investigating eye health. In this work, capillary …

Novel treatments for dry eye syndrome

E Roucaute, M Huertas-Bello, AL Sabater - Current Opinion in …, 2024 - Elsevier
Dry eye syndrome (DES) is a prevalent and multifactorial disease that leads to a self-
perpetuating cycle of inflammation and damage to the ocular surface. This results in …

Multifunctional Cerium Oxide Nanozyme for Synergistic Dry Eye Disease Therapy

H Zou, Y Hong, B Xu, M Wang, H Xie… - ACS Applied Materials …, 2024 - ACS Publications
Dry eye disease (DED) is a chronic multifactorial ocular surface disease mainly caused by
the instability of tear film, characterized by a series of ocular discomforts and even visual …

Vinyl Polymers as Key Materials in Contact Lens Design: A Review of Progress and Future Directions

LM Shaker, A Al‐Amiery, WNRW Isahak… - Starch …, 2024 - Wiley Online Library
Vinyl polymers, crucial in contemporary contact lens design, present unique attributes with
promising implications for vision correction. This comprehensive review navigates the …

Smart Contact Lenses in Ophthalmology: Innovations, Applications, and Future Prospects

KY Wu, A Dave, M Carbonneau, SD Tran - Micromachines, 2024 - mdpi.com
Smart contact lenses represent a breakthrough in the intersection of medical science and
innovative technology, offering transformative potential in ophthalmology. This review article …

Current Advances in Regenerative Strategies for Dry Eye Diseases: A Comprehensive Review

B Bhujel, SH Oh, CM Kim, YJ Yoon, HS Chung, EA Ye… - Bioengineering, 2023 - mdpi.com
Dry eye disease (DED) is an emerging health issue affecting millions of individuals annually.
Ocular surface disorders, such as DED, are characterized by inflammation triggered by …

How does ocular graft‐versus‐host disease fit under the dry eye umbrella? A review

NB Kantor, A Tovar, T Wang… - Clinical & experimental …, 2024 - Wiley Online Library
Graft‐versus‐host disease (GVHD) is a systemic disease that can affect multiple organs as a
consequence of an allogeneic haematopoietic stem cell transplant. One organ system that is …

JAK1, SKI, ZBTB16 as potential biomarkers mediate the inflammatory response in keratoconjunctivitis sicca

Z Dong, C Wang, S Dou, X Yang, D Wang, K Shi, N Wu - Gene, 2024 - Elsevier
Keratoconjunctivitis sicca (KCS) is an ocular condition characterized by insufficient tear
production and inflammatory irritation, with Sjögren's syndrome (SS) being a major …