Therapeutic potential of phenolic compounds in medicinal plants—Natural health products for human health

W Sun, MH Shahrajabian - Molecules, 2023 - mdpi.com
Phenolic compounds and flavonoids are potential substitutes for bioactive agents in
pharmaceutical and medicinal sections to promote human health and prevent and cure …

Ferulic acid: A review of its pharmacology, pharmacokinetics and derivatives

D Li, Y Rui, S Guo, F Luan, R Liu, N Zeng - Life sciences, 2021 - Elsevier
Ferulic acid, a kind of phenolic substance widely existing in plants, is an important active
component of many traditional Chinese medicines. So far, it has been proved that ferulic …

Ferulic acid and feruloylated oligosaccharides alleviate anxiety and depression symptom via regulating gut microbiome and microbial metabolism

L Deng, X Zhou, G Tao, W Hao, L Wang, Z Lan… - Food Research …, 2022 - Elsevier
Incidence of anxiety and depression has been surging in recent years, causing unignorable
mental health crisis across the globe. Mounting studies demonstrated that overgrowth of …

Ferulic acid ameliorates hepatic inflammation and fibrotic liver injury by inhibiting PTP1B activity and subsequent promoting AMPK phosphorylation

J Wu, X Xue, G Fan, Y Gu, F Zhou, Q Zheng… - Frontiers in …, 2021 - frontiersin.org
Chronic inflammation in response to persistent exogenous stimuli or damage results in liver
fibrosis, which subsequently progresses into malignant liver diseases with high morbidity …

Antioxidant therapy against TGF‐β/SMAD pathway involved in organ fibrosis

S Ghafouri‐Fard, A Askari, H Shoorei… - Journal of Cellular …, 2024 - Wiley Online Library
Fibrosis refers to excessive build‐up of scar tissue and extracellular matrix components in
different organs. In recent years, it has been revealed that different cytokines and …

Therapeutic effects and molecular mechanisms of bioactive compounds against respiratory diseases: traditional Chinese medicine theory and high-frequency use

J Wang, Q Wu, L Ding, S Song, Y Li, L Shi… - Frontiers in …, 2021 - frontiersin.org
Respiratory diseases, especially the pandemic of respiratory infectious diseases and
refractory chronic lung diseases, remain a key clinical issue and research hot spot due to …

Ferulic acid: a review of pharmacology, toxicology, and therapeutic effects on pulmonary diseases

Y Zhai, T Wang, Y Fu, T Yu, Y Ding, H Nie - International Journal of …, 2023 - mdpi.com
Ferulic acid (FA), a prevalent dietary phytochemical, has many pharmacological effects,
including anti-oxidation and anti-inflammation effects, and has been widely used in the …

Ferulic acid supplementation alleviates hyperuricemia in high-fructose/fat diet-fed rats via promoting uric acid excretion and mediating the gut microbiota

N Zhang, J Zhou, L Zhao, Z Zhao, S Wang, L Zhang… - Food & Function, 2023 - pubs.rsc.org
The prevalence of hyperuricemia (HUA) has been rising, and it is typically accompanied by
renal injury and intestinal flora disorder, leading to a non-negligible health crisis. Ferulic …

Inhibition of oncogenic src ameliorates silica-induced pulmonary fibrosis via PI3K/AKT pathway

X Hao, Y Jin, Y Zhang, S Li, J Cui, H He, L Guo… - International Journal of …, 2023 - mdpi.com
Silicosis is a refractory disease. Previous studies indicate that damaged alveolar epithelial
cells act as a driver in pulmonary fibrosis. Our results show that epithelial cells that acquire …

A systematic review of the research progress of traditional Chinese medicine against pulmonary fibrosis: from a pharmacological perspective

S Qin, P Tan, J Xie, Y Zhou, J Zhao - Chinese Medicine, 2023 - Springer
Pulmonary fibrosis is a chronic progressive interstitial lung disease caused by a variety of
etiologies. The disease can eventually lead to irreversible damage to the lung tissue …