The oral route is the most common route for drug administration. It is the most preferred
route, due to its advantages, such as non-invasiveness, patient compliance and …

Various diseases remain untreated due to lack of suitable therapeutic moiety or a suitable
drug delivery device, especially where toxicities and side effects are the primary reason for …

Drugs with low water solubility are predisposed to low and variable oral bioavailability and,
therefore, to variability in clinical response. Despite significant efforts to “design in” …

Milling involves the application of mechanical energy to physically break down coarse
particles to finer ones and is regarded as a “top–down” approach in the production of fine …

The formulation of drugs is carried out with the principle objective of enhancing their
bioavailability. Poorly water soluble drugs are challenging for the formulation scientists with …

Poorly water‐soluble drug candidates are becoming more prevalent. It has been estimated
that approximately 60–70% of the drug molecules are insufficiently soluble in aqueous …

Recently, nanotechnology is involved in various fields of science, of which medicine is one
of the most obvious. The use of nanoparticles in the process of treating and diagnosing …

Oral lipid-based drug delivery systems may include a broad range of oils, surfactants, and
cosolvents. This diversity makes comparison of lipid-based formulations difficult. Although …

Poor drug solubility remains a significant and frequently encountered problem for
pharmaceutical scientists. The ability of lipid-based formulations to facilitate gastrointestinal …

The Lipid Formulation Classification System Consortium is an industry–academia
collaboration, established to develop standardized in vitro methods for the assessment of …