Major depressive disorder (MDD) is characterized by persistent depressed mood, loss of
interest or pleasure in previously enjoyable activities, recurrent thoughts of death, and …

A meta-analysis showed a significant association between activated immune-inflammatory
and nitro-oxidative (IO&NS) pathways and suicide attempts (SA). There is no data on …

Microglia survey brain parenchyma, responding to injury and infections. Microglia also
respond to systemic disease, but the role of blood–brain barrier (BBB) integrity in this …

Introduction: The microbiota-gut brain (MGB) axis is the bidirectional communication
between the intestinal microbiota and the brain. An increasing body of preclinical and …

Mental disorders including depression and anxiety are often comorbid with gut problems,
suggesting a bidirectional relationship between mental health and gut function. Several …

Reduced gut-microbial diversity (“gut dysbiosis”) has been associated with an anhedonic/
amotivational syndrome (“sickness behavior”) that manifests across severe mental disorders …

A good nutritional status is important for maintaining normal body function and preventing or
mitigating the dysfunction induced by internal or external factors. Nutritional deficiencies …

Prevalence of mental disorders, including major depressive disorder (MDD), bipolar
disorder (BD) and schizophrenia (SZ) are increasing at alarming rates in our societies …

A growing body of evidence supports an important role for alterations in the brain-gut-
microbiome axis in the aetiology of depression and other psychiatric disorders. The potential …

Statins, which are widely used to treat hypercholesterolemia, have anti-inflammatory and
anti-oxidant effects. These are thought to be responsible for the potential effects of statins on …