[HTML][HTML] Stable gastric pentadecapeptide BPC 157—Possible novel therapy of glaucoma and other ocular conditions

P Sikiric, A Kokot, T Kralj, M Zlatar, S Masnec, R Lazic… - Pharmaceuticals, 2023 - mdpi.com
Recently, stable gastric pentadecapeptide BPC 157 therapy by activation of collateral
pathways counteracted various occlusion/occlusion-like syndromes, vascular, and …

Sensorimotor integration and pain perception: mechanisms integrating nociceptive processing. A systematic review and ALE-meta analysis

C Gombaut, SA Holmes - Frontiers in Integrative Neuroscience, 2022 - frontiersin.org
Pain treatment services and clinical indicators of pain chronicity focus on afferent
nociceptive projections and psychological markers of pain perception with little focus on …

Retinal ganglion cells: global number, density and vulnerability to glaucomatous injury in common laboratory mice

M Claes, L Moons - Cells, 2022 - mdpi.com
How many RBPMS+ retinal ganglion cells (RGCs) does a standard C57BL/6 laboratory
mouse have on average and is this number substrain-or sex-dependent? Do RGCs of …

Stable gastric pentadecapeptide BPC 157 therapy of rat glaucoma

T Kralj, A Kokot, M Zlatar, S Masnec, K Kasnik Kovac… - Biomedicines, 2021 - mdpi.com
Cauterization of three episcleral veins (open-angle glaucoma model) induces venous
congestion and increases intraocular pressure in rats. If not upgraded, one episcleral vein is …

7, 8-Dihydroxiflavone maintains retinal functionality and protects various types of RGCs in adult rats with optic nerve transection

A Gallego-Ortega, B Vidal-Villegas… - International Journal of …, 2021 - mdpi.com
To analyze the neuroprotective effects of 7, 8-Dihydroxyflavone (DHF) in vivo and ex vivo,
adult albino Sprague-Dawley rats were given a left intraorbital optic nerve transection (IONT) …

Retinal changes in astrocytes and Müller Glia in a mouse model of laser-induced glaucoma: a time-course study

JA Fernández-Albarral, R de Hoz, JA Matamoros… - Biomedicines, 2022 - mdpi.com
Macroglia (astrocytes and Müller glia) may play an important role in the pathogenesis of
glaucoma. In a glaucoma mouse model, we studied the effects of unilateral laser-induced …

Axonal injuries cast long shadows: Long term glial activation in injured and contralateral retinas after unilateral axotomy

MJ González-Riquelme, C Galindo-Romero… - International Journal of …, 2021 - mdpi.com
Background: To analyze the course of microglial and macroglial activation in injured and
contralateral retinas after unilateral optic nerve crush (ONC). Methods: The left optic nerve of …

Srgap2 suppression ameliorates retinal ganglion cell degeneration in mice

YJ Gan, Y Cao, ZH Zhang, J Zhang… - Neural Regeneration …, 2023 - journals.lww.com
Abstract Slit-Robo GTPase-activating protein 2 (SRGAP2) plays important roles in axon
guidance, neuronal migration, synapse formation, and nerve regeneration. However, the …

Neuroinflammation and gliosis in the injured and contralateral retinas after unilateral optic nerve crush

JM Cabrera-Maqueda, R Boia, F Lucas-Ruiz… - Experimental Eye …, 2023 - Elsevier
The main purpose of this study is to analyze the effects of unilateral optic nerve crush in the
gene expression of pro-and anti-inflammatory mediators, and gliosis markers in injured and …

Contralateral Astrocyte Response to Acute Optic Nerve Damage Is Mitigated by PANX1 Channel Activity

JA Wurl, CE Mac Nair, JA Dietz, VI Shestopalov… - International Journal of …, 2023 - mdpi.com
Glial reactivity is considered a hallmark of damage-induced innate immune responses in the
central nervous system. In the visual system, unilateral optic nerve damage elicits dramatic …