[HTML][HTML] The involvement of cysteine-X-cysteine motif chemokine receptors in skin homeostasis and the pathogenesis of allergic contact dermatitis and psoriasis

W Liu - International Journal of Molecular Sciences, 2024 - mdpi.com
Members of the CXC motif chemokine receptor (CXCR) superfamily play central roles in
initiating the innate immune response in mammalian cells by orchestrating selective cell …

From gut to skin: exploring the potential of natural products targeting microorganisms for atopic dermatitis treatment

H Zhao, X Ma, J Song, J Jiang, X Fei, Y Luo, Y Ru… - Food & Function, 2023 - pubs.rsc.org
Atopic dermatitis (AD) is the most common chronic inflammatory skin disease. Recent
studies have revealed that interactions between pathogenic microorganisms, which have a …

[HTML][HTML] Biomarkers for phenotype-endotype relationship in atopic dermatitis: a critical review

CO Park, SM Kim, KH Lee, T Bieber - EBioMedicine, 2024 - thelancet.com
Atopic dermatitis (AD) is the most common form of chronic skin inflammation with diverse
clinical variants. Historically, various AD phenotypes have been grouped together without …

Lead Optimization of Butyrolactone I as an Orally Bioavailable Antiallergic Agent Targeting FcγRIIB

CL Xie, HX Xiao, PF Song, QM Liu, H Wei… - Journal of Medicinal …, 2024 - ACS Publications
Food allergy (FA) poses a growing global food safety concern, yet no effective cure exists in
clinics. Previously, we discovered a potent antifood allergy compound, butyrolactone I (BTL …

[HTML][HTML] Single-cell sequencing analysis and multiple machine-learning models revealed the cellular crosstalk of dendritic cells and identified FABP5 and KLRB1 as …

Z Ma, P An, S Hao, Z Huang, A Yin, Y Li… - Frontiers in …, 2024 - frontiersin.org
Background Psoriasis is an immune-mediated disorder influenced by environmental factors
on a genetic basis. Despite advancements, challenges persist, including the diminishing …

Diosmetin ameliorates psoriasis-associated inflammation and keratinocyte hyperproliferation by modulation of PGC-1α/YAP signaling pathway

D Yang, M Peng, F Fu, W Zhao, B Zhang - International …, 2024 - Elsevier
Psoriasis, characterized by aberrant epidermal keratinocyte proliferation and differentiation,
is a chronic inflammatory immune-related skin disease. Diosmetin (Dios), derived from citrus …

Treatment of atopic dermatitis: Recently approved drugs and advanced clinical development programs

S Müller, L Maintz, T Bieber - Allergy, 2024 - Wiley Online Library
Atopic dermatitis (AD) represents the most common skin disease characterized by
heterogeneous endophenotypes and a high disease burden. In Europe, six new systemic …

[HTML][HTML] Air pollution and skin diseases: A comprehensive evaluation of the associated mechanism

X Gu, Z Li, J Su - Ecotoxicology and Environmental Safety, 2024 - Elsevier
Air pollutants deteriorate the survival environment and endanger human health around the
world. A large number of studies have confirmed that air pollution jeopardizes multiple …

Interleukin antagonists for atopic dermatitis: a new era of therapy

A Tsiogka, E Paschou, D Koumaki… - Expert Opinion on …, 2024 - Taylor & Francis
Introduction Over the last decade, increasing understanding of the immunopathogenesis of
atopic dermatitis (AD) enabled the recognition of multiple therapeutic targets and …

[HTML][HTML] A novel portable in situ printer for hydrogel multi-structure molding and cell printing

H Liu, Y Zhang, Z Jian, C Gao, C Lu, Q Dai… - APL …, 2023 - pubs.aip.org
Skin lesions not only disrupt appearance and barrier functionality but also lead to severe
microbial infections and immune-inflammatory responses, seriously affect physical and …