In eons of evolution, isocyanides carved out a niche in the ecological systems probably
thanks to their metal coordinating properties. In 1859 the first isocyanide was synthesized by …

Covering: 2015. Previous review: Nat. Prod. Rep., 2016, 33, 382–431 This review covers the
literature published in 2015 for marine natural products (MNPs), with 1220 citations (792 for …

Background Malaria remains a significant public health challenge in regions of the world
where it is endemic. An unprecedented decline in malaria incidences was recorded during …

The systematic review of the marine pharmacology literature from 2014 to 2015 was
completed in a manner consistent with the 1998–2013 reviews of this series. Research in …

This review covers the literature published in 2015 for marine natural products (MNPs), with
1220 citations (792 for the period January to December 2015) referring to compounds …

Natural products have made a crucial and unique contribution to human health, and this is
especially true in the case of malaria, where the natural products quinine and artemisinin …

Abstract The Pathogen Box is a 400‐strong collection of drug‐like compounds, selected for
their potential against several of the world's most important neglected tropical diseases …

Fragment coupling reactions that form carbon–carbon bonds are valuable transformations in
synthetic design. Advances in metal‐catalyzed cross‐coupling reactions in the early 2000s …

Marine isonitriles represent the largest group of natural products carrying the remarkable
isocyanide moiety. Together with marine isothiocyanates and formamides, which originate …

7, 20-Diisocyanoadociane, a scarce marine metabolite with potent antimalarial activity, was
synthesized as a single enantiomer in 13 steps from simple building blocks (17 linear steps) …