Separable effects for causal inference in the presence of competing events

MJ Stensrud, JG Young, V Didelez… - Journal of the …, 2022 - Taylor & Francis
In time-to-event settings, the presence of competing events complicates the definition of
causal effects. Here we propose the new separable effects to study the causal effect of a …

[HTML][HTML] PSHREG: a SAS macro for proportional and nonproportional subdistribution hazards regression

M Kohl, M Plischke, K Leffondré, G Heinze - Computer methods and …, 2015 - Elsevier
We present a new SAS macro% pshreg that can be used to fit a proportional subdistribution
hazards model for survival data subject to competing risks. Our macro first modifies the input …

Blood lipids and lipoproteins in relation to incidence and mortality risks for CVD and cancer in the prospective EPIC–Heidelberg cohort

VA Katzke, D Sookthai, T Johnson, T Kühn, R Kaaks - BMC medicine, 2017 - Springer
Background Circulating concentrations of lipid biomarkers are associated with risk of
cardiovascular diseases (CVD). The evidence for a relationship with cancer risk, however, is …

Outcomes of patients lost to follow-up in African antiretroviral therapy programs: individual patient data meta-analysis

F Chammartin, K Zürcher, O Keiser… - Clinical infectious …, 2018 - academic.oup.com
Background Low retention on combination antiretroviral therapy (cART) has emerged as a
threat to the Joint United Nations Programme on human immunodeficiency virus (HIV)/AIDS …

Intrauterine device-related uterine perforation incidence and risk (APEX-IUD): a large multisite cohort study

SD Reed, X Zhou, L Ichikawa, JL Gatz, JF Peipert… - The Lancet, 2022 - thelancet.com
Background Reports of perforation risk related to intrauterine devices (IUDs) inserted
immediately post partum and among non-post-partum individuals are scarce, and previous …

Self-harm in a primary care cohort of older people: incidence, clinical management, and risk of suicide and other causes of death

C Morgan, RT Webb, MJ Carr, E Kontopantelis… - The Lancet …, 2018 - thelancet.com
Background Self-harm is a major risk factor for suicide, with older adults (older than 65
years) having reportedly greater suicidal intent than any other age group. With the aging …

Flexible parametric modelling of cause-specific hazards to estimate cumulative incidence functions

SR Hinchliffe, PC Lambert - BMC medical research methodology, 2013 - Springer
Background Competing risks are a common occurrence in survival analysis. They arise
when a patient is at risk of more than one mutually exclusive event, such as death from …

Thromboembolic and bleeding complications during oral anticoagulation therapy in cancer patients with atrial fibrillation: a Danish nationwide population‐based …

AG Ording, E Horváth‐Puhó, K Adelborg… - Cancer …, 2017 - Wiley Online Library
Coexisting cancer in patients with atrial fibrillation (AF) has been associated with
thromboembolism and bleeding. We used Danish population‐based medical databases to …

Decomposition of number of life years lost according to causes of death

PK Andersen - Statistics in medicine, 2013 - Wiley Online Library
We study the competing risks model and show that the cause j cumulative incidence function
integrated from 0 to τ has a natural interpretation as the expected number of life years lost …

Individual participant data meta‐analysis of intervention studies with time‐to‐event outcomes: a review of the methodology and an applied example

VMT de Jong, KGM Moons, RD Riley… - Research synthesis …, 2020 - Wiley Online Library
Many randomized trials evaluate an intervention effect on time‐to‐event outcomes.
Individual participant data (IPD) from such trials can be obtained and combined in a so …