Biological activities of ruthenium NHC complexes: An update

A Catalano, A Mariconda, MS Sinicropi, J Ceramella… - Antibiotics, 2023 - mdpi.com
Ruthenium N-heterocyclic carbene (NHC) complexes have unique physico-chemical
properties as catalysts and a huge potential in medicinal chemistry and pharmacology …

N-Heterocyclic carbene complexes of Au (I), Ag (I), and Cu (I) as potential anticancer agents: a review

A Alsalhi - Journal of Coordination Chemistry, 2023 - Taylor & Francis
The discovery of cisplatin antitumor properties in 1969 encouraged researchers to design
metal-based anticancer drugs. Recently, research on N-heterocyclic carbene-based metal …

O-Halogen-substituted arene linked selenium-N-heterocyclic carbene compounds induce significant cytotoxicity: Crystal structures and molecular docking studies

K Hayat, M Shkeel, MA Iqbal, CK Quah… - Journal of …, 2023 - Elsevier
Synthesis of N-arylated benzimidazolium salts 1–2, as stable N-heterocyclic Carbene (NHC)
σ-donor ligands, was carried out by simple, facile and high yielding method. Respective Se …

N-heterocyclic carbene based Bi-nuclear organoselenium compounds impart a mild biocidal potential compared to their ligands: Synthesis, characterization …

A Hassan, MA Iqbal, HN Bhatti, M Shahid - Computational Biology and …, 2023 - Elsevier
N-heterocyclic carbene (NHC) based compounds are remarkably known for astonishing
biological potentials. Coordination of metal center with these compounds can substantially …

Design, synthesis, spectroscopic characterizations, single crystal X-ray analysis, in vitro xanthine oxidase and acetylcholinesterase inhibitory evaluation as well as in silico …

G Kaya, SAA Noma, D Barut Celepci… - Journal of …, 2023 - Taylor & Francis
Herein, eight new NHC-based selenourea derivatives were synthesized and characterized
by using spectroscopic method (1H, 19F, and 13C NMR, FT-IR), and elemental analysis …

Cytotoxic, Thrombolytic and Antibacterial Evaluation of Synthesized Substituted and Un-Substituted Selenium-N-Heterocyclic Carbene Adducts.

A Kamal, MA Iqbal, HN Bhatti… - Journal of the Chemical …, 2023 - search.ebscohost.com
Alkyl-substituted azolium salts (1-8) and their Se-N-heterocyclic carbene (Se-N-Het-C)
adducts (9-12) were obtained in very reasonable yields. All synthesized azolium salts and …

Biological potential of vinyl/allyl substituted imidazole-based N-heterocyclic carbene adducts: synthesis, spectral and X-ray crystallographic structural characteristics

A Kamal, AH Ibrahim, SS Al-Rawi, MA Iqbal, HN Bhatti - Chemical Papers, 2024 - Springer
This manuscript describes the synthesis of three new selenium vinyl/allyl adducts (IV–VI),
which incorporate imidazolium-N-heterocyclic carbene salts (I–III) are. The characterization …

Preparation, Characterization, DFT Calculations, biological evaluations and Molecular docking studies of benzimidazolium-based N-heterocyclic carbenes and …

A Altaf, F Jamil, M Yaqoob, MA Iqbal, S Sadique… - Inorganica Chimica …, 2025 - Elsevier
This study involves designing through DFT, synthesis, and characterization of three
benzimidazolium salts (AL1-AL3) and their corresponding selenium adducts (AC1-AC3) …

Theoretical and experimental investigation of N-alkyl substituted bis-imidazolium salts and their binuclear N-heterocyclic carbene silver acetate complexes

M Yaqoob, MA Iqbal, HN Bhatti… - Journal of Coordination …, 2023 - Taylor & Francis
Our research centers on structural, biological, and electronic properties of N-heterocyclic
carbene salts and their silver acetate-based complexes. After theoretical calculations …

Synthesis, and study biological activity of CuI complexes involving imidazole-2-selones as ligands

AH Mageed, WH Ali - Journal of Organometallic Chemistry, 2023 - Elsevier
A series of imidazole-2-selone (IMSe) ligands were synthesized by reacting of bis-
imidazolium salts with selenium in the presence of mild base. These lignads were treated …