Copy number variants (CNVs) are regions of the genome that vary in integer copy number.
CNVs, which comprise both amplifications and deletions of DNA sequence, have been …

The division of the cellular space into nucleoplasm and cytoplasm promotes quality control
mechanisms that prevent misprocessed mRNAs and junk RNAs from gaining access to the …

The off-target toxicity of drugs targeted to proteins imparts substantial health and economic
costs. Proteome interaction studies can reveal off-target effects with unintended proteins; …

Thousands of species will be sequenced in the next few years; however, understanding how
their genomes work, without an unlimited budget, requires both molecular and novel …

Non-allelic recombination between homologous repetitive elements contributes to evolution
and human genetic disorders. Here, we combine short-and long-DNA read sequencing of …

The field of population genomics has seen a surge of studies on genomic structural variation
over the past two decades. These studies witnessed that structural variation is taxonomically …

Being activated by endogenous and exogenous ligands, nuclear receptor peroxisome
proliferator-activated receptor gamma (PPARγ) enhances insulin sensitivity, promotes …

Despite polymorphic duplicate genes' importance for the early stages of duplicate gene
evolution, they are less studied than old gene duplicates. Two essential questions thus …

The increasing incidence of ischemic stroke emphasizes the necessity for early detection
and preventive strategies. Diagnostic biomarkers currently available for ischemic stroke only …

In self-renewing somatic tissue such as skin epidermis, terminal differentiation genes must
be suppressed in progenitors to sustain regenerative capacity. Here we show that hundreds …