Sodium‐glucose cotransporter‐2 inhibitors and kidney outcomes in real‐world type 2 diabetes populations: a systematic review and meta‐analysis of observational …

AK Forbes, RJ Suckling, W Hinton… - Diabetes, Obesity …, 2023 - Wiley Online Library
Aim To conduct a systematic review of observational studies to explore the real‐world
kidney benefits of sodium‐glucose cotransporter‐2 (SGLT2) inhibitors in a large and diverse …

[HTML][HTML] Treatment effect heterogeneity following type 2 diabetes treatment with GLP1-receptor agonists and SGLT2-inhibitors: a systematic review

KG Young, EH McInnes, RJ Massey… - Communications …, 2023 - nature.com
Background A precision medicine approach in type 2 diabetes requires the identification of
clinical and biological features that are reproducibly associated with differences in clinical …

Efficacy/safety balance of DPP-4 inhibitors versus SGLT2 inhibitors in elderly patients with type 2 diabetes

AJ Scheen - Diabetes & metabolism, 2021 - Elsevier
Abstract Dipeptidyl peptidase-4 inhibitors (DPP-4is) and sodium-glucose cotransporter type
2 inhibitors (SGLT2is) offer new options for the oral management of type 2 diabetes mellitus …

Cardiovascular, renal, and lower limb outcomes in patients with type 2 diabetes after percutaneous coronary intervention and treated with sodium–glucose …

HF Lee, YH Chan, C Chuang, PR Li… - European Heart …, 2023 - academic.oup.com
Aims Patients with type 2 diabetes (T2D) who undergo percutaneous coronary intervention
(PCI) are at higher risk of adverse cardiovascular and renal events than non-diabetic …

[HTML][HTML] Long-term benefits of dapagliflozin on renal outcomes of type 2 diabetes under routine care: a comparative effectiveness study on propensity score matched …

GP Fadini, E Longato, ML Morieri… - The Lancet Regional …, 2024 - thelancet.com
Background Despite the overall improvement in care, people with type 2 diabetes (T2D)
experience an excess risk of end-stage kidney disease. We evaluated the long-term …

[HTML][HTML] Long-term, real-world kidney outcomes with SGLT2i versus DPP4i in type 2 diabetes without cardiovascular or kidney disease

CM Cohen, M Schechter, A Rozenberg… - Clinical Journal of the …, 2023 - journals.lww.com
Background Contemporary guidelines recommend the use of sodium-glucose cotransporter
2 inhibitors (SGLT2is) independently of glycemic control in patients with type 2 diabetes and …

Sodium‐glucose co‐transporter‐2 inhibitors in type 2 diabetes: Are clinical trial benefits for heart failure reflected in real‐world clinical practice? A systematic review …

W Hinton, AS Ansari, MB Whyte… - Diabetes, Obesity …, 2023 - Wiley Online Library
Aim To determine the absolute risk reduction (ARR) of heart failure events in people treated
with sodium‐glucose co‐transporter‐2 (SGLT2) inhibitors. Materials and Methods We …

[HTML][HTML] Precision medicine in type 2 diabetes: A systematic review of treatment effect heterogeneity for GLP1-receptor agonists and SGLT2-inhibitors

KG Young, EH McInnes, RJ Massey, AR Kahkohska… - medRxiv, 2023 - ncbi.nlm.nih.gov
Background: A precision medicine approach in type 2 diabetes requires identification of
clinical and biological features that are reproducibly associated with differences in clinical …

Challenges and opportunities in real‐world evidence on the renal effects of sodium‐glucose cotransporter‐2 inhibitors

GP Fadini, S Del Prato, A Avogaro… - Diabetes, Obesity and …, 2022 - Wiley Online Library
With increasing population aging and prevalence of type 2 diabetes (T2D) worldwide,
prevention of diabetic complications remains a major unmet need. While cardiovascular …

Significant reduction in chronic kidney disease progression with sodium‐glucose cotransporter‐2 inhibitors compared to dipeptidyl peptidase‐4 inhibitors in adults …

I Idris, R Zhang, JB Mamza, M Ford… - Diabetes, Obesity …, 2022 - Wiley Online Library
Aims To confirm the reno‐protective effects of sodium‐glucose cotransporter‐2 (SGLT2)
inhibitors compared with dipeptidyl peptidase‐4 (DPP‐4) inhibitors on the onset and …