The human gastrointestinal tract is populated with a diverse microbial community. The vast
genetic and metabolic potential of the gut microbiome underpins its ubiquity in nearly every …

Alzheimer's disease (AD) is a major cause of dementia in older adults and is fast becoming
a major societal and economic burden due to an increase in life expectancy. Age seems to …

Background The regulatory mechanisms involved in mitochondrial quality control (MQC)
dysfunction during septic cardiomyopathy (SCM) remain incompletely characterized …

Alzheimer's disease (AD) is a devastating neurodegenerative disorder characterized by the
deposition of β-amyloid (Aβ) peptides and dysfunction of mitochondrion, which result in …

Mitochondrial dysfunction of neurons is the core pathogenesis of incurable Parkinson's
disease (PD). It is crucial to ameliorate the mitochondrial dysfunction of neurons for boosting …

Rosacea is significantly associated with dementia, particularly Alzheimer's disease (AD).
However, the common underlying molecular mechanism connecting these two diseases …

Sickle cell disease (SCD), a distinctive and often overlooked illness in the 21st century, is a
congenital blood disorder characterized by considerable phenotypic diversity. It comprises a …

Excessive expansion of adipocytes can have unhealthy consequences as excess free fatty
acids enter other tissues and cause ectopic fat deposition by resynthesizing triglycerides …

Millions of people worldwide are affected by neurodegenerative diseases (NDs). NDs are
characterized by progressive damage and death of nerve cells accompanied by high levels …

The α-synucleinopathies constitute a subset of neurodegenerative disorders, of which
Parkinson's disease (PD) is the most common worldwide, characterized by the accumulation …