Neuronal cell death
M Fricker, AM Tolkovsky, V Borutaite… - Physiological …, 2018 - journals.physiology.org
Neuronal cell death occurs extensively during development and pathology, where it is
especially important because of the limited capacity of adult neurons to proliferate or be …
especially important because of the limited capacity of adult neurons to proliferate or be …
The role of NLRP3 inflammasome in cerebrovascular diseases pathology and possible therapeutic targets
R Bai, Y Lang, J Shao, Y Deng, R Refuhati… - ASN neuro, 2021 - journals.sagepub.com
Cerebrovascular diseases are pathological conditions involving impaired blood flow in the
brain, primarily including ischaemic stroke, intracranial haemorrhage, and subarachnoid …
brain, primarily including ischaemic stroke, intracranial haemorrhage, and subarachnoid …
Preserved structural connectivity mediates the clinical effect of thrombolysis in patients with anterior-circulation stroke
E Schlemm, T Ingwersen, A Königsberg… - Nature …, 2021 - nature.com
Thrombolysis with recombinant tissue plasminogen activator in acute ischemic stroke aims
to restore compromised blood flow and prevent further neuronal damage. Despite the …
to restore compromised blood flow and prevent further neuronal damage. Despite the …
Determination of the therapeutic time window for human umbilical cord blood mononuclear cell transplantation following experimental stroke in rats
J Boltze, UR Schmidt, DM Reich, A Kranz… - Cell …, 2012 - journals.sagepub.com
Experimental treatment strategies using human umbilical cord blood mononuclear cells
(hUCB MNCs) represent a promising option for alternative stroke therapies. An important …
(hUCB MNCs) represent a promising option for alternative stroke therapies. An important …
Assessment of neuroprotective effects of human umbilical cord blood mononuclear cell subpopulations in vitro and in vivo
J Boltze, DM Reich, S Hau, KG Reymann… - Cell …, 2012 - journals.sagepub.com
Experimental transplantation of human umbilical cord blood (hUCB) mononuclear cells
(MNCs) in rodent stroke models revealed the therapeutic potential of these cells. However …
(MNCs) in rodent stroke models revealed the therapeutic potential of these cells. However …
Present status of magnetic resonance imaging and spectroscopy in animal stroke models
R Weber, P Ramos-Cabrer… - Journal of Cerebral Blood …, 2006 - journals.sagepub.com
Magnetic resonance imaging (MRI) is based on a wide variety of physical parameters,
which, in principle, can all influence the image contrast conditions. As these diverse …
which, in principle, can all influence the image contrast conditions. As these diverse …
Neuroprotection of cerebrolysin in tissue culture models of brain ischemia: post lesion application indicates a wide therapeutic window
E Schauer, R Wronski, J Patockova, H Moessler… - Journal of Neural …, 2006 - Springer
All attempts to reduce neuronal damage after acute brain ischemia by the use of
neuroprotective compounds have failed to prove efficacy in clinical trials so far. One of the …
neuroprotective compounds have failed to prove efficacy in clinical trials so far. One of the …
Ischemic post-conditioning and vasodilator therapy during standard cardiopulmonary resuscitation to reduce cardiac and brain injury after prolonged untreated …
Aim of the study We investigated the effects of ischemic postconditioning (IPC) with and
without cardioprotective vasodilatory therapy (CVT) at the initiation of cardiopulmonary …
without cardioprotective vasodilatory therapy (CVT) at the initiation of cardiopulmonary …
Endothelial microparticle levels are similar in acute ischemic stroke and stroke mimics due to activation and not apoptosis/necrosis
JB Williams, EC Jauch, CJ Lindsell… - Academic Emergency …, 2007 - Wiley Online Library
BackgroundEndothelial microparticles (EMPs) are< 2‐μm membranous blebs from
endothelial cell membranes that have been demonstrated to be elevated in vasculopathic …
endothelial cell membranes that have been demonstrated to be elevated in vasculopathic …
Effects of sodium nitroprusside administered via a subdural intracranial catheter on the microcirculation, oxygenation, and electrocortical activity of the cerebral cortex …
HY Lee, YH Jung, N Mamadjonov… - Journal of the …, 2022 - Am Heart Assoc
Background Postischemic cerebral hypoperfusion has been indicated as an important
contributing factor to secondary cerebral injury after cardiac arrest. We evaluated the effects …
contributing factor to secondary cerebral injury after cardiac arrest. We evaluated the effects …