Glioblastoma (GBM) is a particularly devastating tumor with a median survival of about 16
months. Recent research has revealed novel insights into the outstanding heterogeneity of …

Glioblastoma extensively infiltrates the brain; despite surgery and aggressive therapies, the
prognosis is poor. A multidisciplinary approach combining mathematical, clinical and …

Abstract Treatment planning in radiotherapy distinguishes three target volume concepts: the
gross tumor volume (GTV), the clinical target volume (CTV), and the planning target volume …

The broad possibilities offered by microfluidic devices in relation to massive data monitoring
and acquisition open the door to the use of deep learning technologies in a very promising …

Glioblastoma cells adopt migration strategies to invade into the brain parenchyma ranging
from individual to collective mechanisms, whose role and dynamics are not yet fully …

Cancer is a leading cause of death worldwide and results in nearly 10 million deaths each
year. The global economic burden of cancer from 2020 to 2050 is estimated to be USD 25.2 …

In this work we analyse a PDE-ODE problem modelling the evolution of a Glioblastoma,
which includes chemotaxis term directed to vasculature. First, we obtain some a priori …

Molecular biomarkers correspond to all endogenous or exogenous biomolecules, whose
presence or alteration in metabolic pathways indicate the response of a biological system to …

Glioblastoma is the most aggressive and infiltrative glioma, classified as Grade IV, with the
poorest survival rate among patients. Accurate and rigorously tested mechanistic in silico …

Simple Summary Biomechanical forces aggravate brain tumor progression. In this study,
magnetic resonance elastography (MRE) is employed to extract tissue biomechanical …