[HTML][HTML] Endothelial dysfunction in COVID-19: an overview of evidence, biomarkers, mechanisms and potential therapies

S Xu, I Ilyas, J Weng - Acta Pharmacologica Sinica, 2023 - nature.com
The fight against coronavirus disease 2019 (COVID-19) caused by SARS-CoV-2 infection is
still raging. However, the pathophysiology of acute and post-acute manifestations of COVID …

[HTML][HTML] The signal pathways and treatment of cytokine storm in COVID-19

L Yang, X Xie, Z Tu, J Fu, D Xu, Y Zhou - Signal transduction and …, 2021 - nature.com
Abstract The Coronavirus Disease 2019 (COVID-19) pandemic has become a global crisis
and is more devastating than any other previous infectious disease. It has affected a …

[HTML][HTML] Role of JAK/STAT in interstitial lung diseases; molecular and cellular mechanisms

P Montero, J Milara, I Roger, J Cortijo - International journal of molecular …, 2021 - mdpi.com
Interstitial lung diseases (ILDs) comprise different fibrotic lung disorders characterized by
cellular proliferation, interstitial inflammation, and fibrosis. The JAK/STAT molecular pathway …

[HTML][HTML] Structural and non-structural proteins in SARS-CoV-2: potential aspects to COVID-19 treatment or prevention of progression of related diseases

S Kakavandi, I Zare, M VaezJalali, M Dadashi… - Cell Communication and …, 2023 - Springer
Abstract Coronavirus disease 2019 (COVID-19) is caused by a new member of the
Coronaviridae family known as severe acute respiratory syndrome coronavirus 2 (SARS …

Epithelial response to IFN‐γ promotes SARS‐CoV‐2 infection

J Heuberger, J Trimpert, D Vladimirova… - EMBO molecular …, 2021 - embopress.org
Abstract SARS‐CoV‐2, the agent that causes COVID‐19, invades epithelial cells, including
those of the respiratory and gastrointestinal mucosa, using angiotensin‐converting enzyme …

[HTML][HTML] Vanadium as potential therapeutic agent for COVID-19: A focus on its antiviral, antiinflamatory, and antihyperglycemic effects

S Semiz - Journal of Trace Elements in Medicine and Biology, 2022 - Elsevier
An increasing evidence suggests that vanadium compounds are novel potential drugs in the
treatment of diabetes, atherosclerosis, and cancer. Vanadium has also demonstrated …

[HTML][HTML] Therapeutic implications of current Janus kinase inhibitors as anti-COVID agents: A review

NK Jain, M Tailang, HK Jain… - Frontiers in …, 2023 - frontiersin.org
Severe cases of COVID-19 are characterized by hyperinflammation induced by cytokine
storm, ARDS leading to multiorgan failure and death. JAK-STAT signaling has been …

Zooming in on common immune evasion mechanisms of pathogens in phagolysosomes: potential broad-spectrum therapeutic targets against infectious diseases

A Selvapandiyan, N Puri, P Kumar… - FEMS Microbiology …, 2023 - academic.oup.com
The intracellular viral, bacterial, or parasitic pathogens evade the host immune challenges to
propagate and cause fatal diseases. The microbes overpower host immunity at various …

[HTML][HTML] Resveratrol as an adjunctive therapy for excessive oxidative stress in aging COVID-19 patients

MT Liao, CC Wu, SFV Wu, MC Lee, WC Hu, KW Tsai… - Antioxidants, 2021 - mdpi.com
The coronavirus disease 2019 (COVID-19) pandemic continues to burden healthcare
systems worldwide. COVID-19 symptoms are highly heterogeneous, and the patient may be …

Tofacitinib reduces mortality in coronavirus disease 2019 Tofacitinib in COVID-19

R Maslennikov, V Ivashkin, E Vasilieva… - Pulmonary …, 2021 - Elsevier
Background and aim Cytokine release syndrome is a dangerous complication of the
coronavirus disease 2019 (COVID-19). This study aimed to evaluate the efficacy and safety …