[HTML][HTML] SARS-CoV-2 and the Nucleus
The ongoing COVID-19 pandemic is caused by an RNA virus, SARS-CoV-2. The genome of
SARS-CoV-2 lacks a nuclear phase in its life cycle and is replicated in the cytoplasm …
SARS-CoV-2 lacks a nuclear phase in its life cycle and is replicated in the cytoplasm …
[HTML][HTML] Nanotechnology to the rescue: treatment perspective for the immune dysregulation observed in COVID-19
AE Peter, BV Sandeep, BG Rao… - Frontiers in …, 2021 - frontiersin.org
The study of the use of nanotechnology for drug delivery has been extensive. Nanomedical
approaches for therapeutics; drug delivery in particular is superior to conventional methods …
approaches for therapeutics; drug delivery in particular is superior to conventional methods …
[PDF][PDF] The exploration of glucocorticoid pathway based on disease severity in COVID-19 patients
Systemic inflammation is a hallmark of Coronavirus Disease 2019 (COVID-19) and is the
key to the pathophysiology of its severe cases with host cytokine involvement …
key to the pathophysiology of its severe cases with host cytokine involvement …
Cardiac auscultation predicts mortality in elderly patients admitted for COVID-19
N Roig-Marín, P Roig-Rico - Hospital Practice, 2022 - Taylor & Francis
Introduction COVID-19 has had a great impact on the elderly population. All admitted
patients underwent cardiac auscultation at the Emergency Department. However, to our …
patients underwent cardiac auscultation at the Emergency Department. However, to our …
[PDF][PDF] ACE2 overexpressing mesenchymal stem cells alleviates COVID-19 lung injury by inhibiting pyroptosis
J Wei, R Shang, J Wang, S Zhu, JQ Yin, Y Chen… - Iscience, 2022 - cell.com
Mesenchymal stem cells (MSCs) have shown some efficacy in the COVID-19 treatment. We
proposed that exogenous supplementation of ACE2 via MSCs (ACE2-MSCs) might have …
proposed that exogenous supplementation of ACE2 via MSCs (ACE2-MSCs) might have …
[HTML][HTML] Integrated network pharmacology analysis and in vitro validation revealed the underlying mechanism of Xiyanping injection in treating coronavirus disease …
J Li, S Guo, Y Tan, J Zhang, Z Wu, A Stalin, F Zhang… - Medicine, 2023 - journals.lww.com
Background: Coronavirus disease 2019 (COVID-19) has spread rapidly worldwide, leading
to a pandemic. In China, Xiyanping injection (XYP) has been recommended as a drug for …
to a pandemic. In China, Xiyanping injection (XYP) has been recommended as a drug for …
[HTML][HTML] The Clinical Analysis of Checkpoint Inhibitor Pneumonitis with Different Severities in Lung Cancer Patients: A Retrospective Study
H Huang, R Chen, Y Xu, N Fang, C Shao, K Xu… - Journal of Clinical …, 2024 - mdpi.com
Immune-related adverse events (irAEs) of immunotherapy would lead to the temporary or
permanent discontinuation of immune checkpoint inhibitors (ICIs). Among them, checkpoint …
permanent discontinuation of immune checkpoint inhibitors (ICIs). Among them, checkpoint …
The association of Sirtuin1 (SIRT1) polymorphism and downregulation of STAT4 gene expression with increased susceptibility to COVID-19 infection
ABSTRACT Sirtuin1 (SIRT1) is an epigenetic modulator that belongs to sirtuins family and
participates in many physiologic reactions, as genomic stabilization, apoptosis, proliferation …
participates in many physiologic reactions, as genomic stabilization, apoptosis, proliferation …
Effect of tofacitinib on clinical and laboratory findings in severe and resistant patients with COVID-19
S Almasi, A Rashidi, MA Kachuee, BM Shirazi… - International …, 2023 - Elsevier
Background The efficacy and safety of a strong Janus kinase inhibitor, tofacitinib, in
individuals suffering from severe coronavirus disease 2019 (Covid-19) pneumonia are not …
individuals suffering from severe coronavirus disease 2019 (Covid-19) pneumonia are not …
[HTML][HTML] Tofacitinib in the treatment of ulcerative colitis: A position paper issued by the Inflammatory Bowel Disease Working Group of the Austrian Society of …
M Kutschera, G Novacek, W Reinisch… - Wiener Klinische …, 2023 - Springer
Ulcerative colitis (UC) is one of the main forms of inflammatory bowel disease (IBD). Despite
the widening range of drug treatment options, primary nonresponse, secondary loss of …
the widening range of drug treatment options, primary nonresponse, secondary loss of …