Non-coding RNAs in disease: from mechanisms to therapeutics

K Nemeth, R Bayraktar, M Ferracin… - Nature Reviews Genetics, 2024 - nature.com
Non-coding RNAs (ncRNAs) are a heterogeneous group of transcripts that, by definition, are
not translated into proteins. Since their discovery, ncRNAs have emerged as important …

2023 guideline for the management of patients with aneurysmal subarachnoid hemorrhage: a guideline from the American Heart Association/American Stroke …

BL Hoh, NU Ko, S Amin-Hanjani, SHY Chou… - Stroke, 2023 - Am Heart Assoc
Aim: The “2023 Guideline for the Management of Patients With Aneurysmal Subarachnoid
Hemorrhage” replaces the 2012 “Guidelines for the Management of Aneurysmal …

2023 ACC/AHA/ACCP/HRS guideline for the diagnosis and management of atrial fibrillation: a report of the American College of Cardiology/American Heart …

JA Joglar, MK Chung, AL Armbruster, EJ Benjamin… - Circulation, 2024 - Am Heart Assoc
AIM The “2023 ACC/AHA/ACCP/HRS Guideline for the Diagnosis and Management of Atrial
Fibrillation” provides recommendations to guide clinicians in the treatment of patients with …

[HTML][HTML] Complete or culprit-only PCI in older patients with myocardial infarction

S Biscaglia, V Guiducci, J Escaned… - … England Journal of …, 2023 - Mass Medical Soc
Background The benefit of complete revascularization in older patients (≥ 75 years of age)
with myocardial infarction and multivessel disease remains unclear. Methods In this …

Aldosterone synthase inhibition with lorundrostat for uncontrolled hypertension: the target-HTN randomized clinical trial

LJ Laffin, D Rodman, JM Luther, A Vaidya, MR Weir… - Jama, 2023 - jamanetwork.com
Importance Excess aldosterone production contributes to hypertension in both classical
hyperaldosteronism and obesity-associated hypertension. Therapies that reduce …

[HTML][HTML] Characteristics and outcomes among adults aged≥ 60 years hospitalized with laboratory-confirmed respiratory syncytial virus—RSV-NET, 12 states, July …

FP Havers - MMWR. Morbidity and Mortality Weekly Report, 2023 - cdc.gov
Respiratory syncytial virus (RSV) causes substantial morbidity and mortality in older adults.
In May 2023, two RSV vaccines were approved for prevention of RSV lower respiratory tract …

Global epidemiology of acute coronary syndromes

A Timmis, D Kazakiewicz, N Townsend… - Nature Reviews …, 2023 - nature.com
This Review provides an epidemiological overview of global mortality from acute coronary
syndromes (ACS). Across the regions of the world where data are available, mortality from …

[PDF][PDF] Cardiac macrophages and emerging roles for their metabolism after myocardial infarction

EB Thorp - Journal of Clinical Investigation, 2023 - Am Soc Clin Investig
Interest in cardioimmunology has reached new heights as the experimental cardiology field
works to tap the unrealized potential of immunotherapy for clinical care. Within this space is …

Novel prediction equations for absolute risk assessment of total cardiovascular disease incorporating cardiovascular-kidney-metabolic health: a scientific statement …

SS Khan, J Coresh, MJ Pencina, CE Ndumele… - Circulation, 2023 - Am Heart Assoc
Cardiovascular-kidney-metabolic (CKM) syndrome is a novel construct recently defined by
the American Heart Association in response to the high prevalence of metabolic and kidney …

Economic burden of cardiovascular diseases in the European Union: a population-based cost study

R Luengo-Fernandez, M Walli-Attaei… - European Heart …, 2023 - academic.oup.com
Abstract Background and Aims Cardiovascular disease (CVD) impacts significantly health
and social care systems as well as society through premature mortality and disability, with …