[HTML][HTML] Glutathione deficiency in the pathogenesis of SARS-CoV-2 infection and its effects upon the host immune response in severe COVID-19 disease

CA Labarrere, GS Kassab - Frontiers in Microbiology, 2022 - frontiersin.org
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) that causes coronavirus
disease 19 (COVID-19) has numerous risk factors leading to severe disease with high …

[HTML][HTML] From co-infections to autoimmune disease via hyperactivated innate immunity: COVID-19 autoimmune coagulopathies, autoimmune myocarditis and …

R Root-Bernstein - International Journal of Molecular Sciences, 2023 - mdpi.com
Neutrophilia and the production of neutrophil extracellular traps (NETs) are two of many
measures of increased inflammation in severe COVID-19 that also accompany its …

[HTML][HTML] SARS-CoV-2 modulates inflammatory responses of alveolar epithelial type II cells via PI3K/AKT pathway

AA Al-Qahtani, I Pantazi, FS Alhamlan… - Frontiers in …, 2022 - frontiersin.org
Background SARS-CoV-2 infects through the respiratory route and triggers inflammatory
response by affecting multiple cell types including type II alveolar epithelial cells. SARS-CoV …

An insight overview on COVID-19 mRNA vaccines: advantageous, pharmacology, mechanism of action, and prospective considerations

MS Mirtaleb, R Falak, J Heshmatnia… - International …, 2023 - Elsevier
The worldwide spread of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)
has urged scientists to present some novel vaccine platforms during this pandemic to …

[HTML][HTML] Drug repurposing for the treatment of COVID-19: Targeting nafamostat to the lungs by a liposomal delivery system

P Reus, H Guthmann, N Uhlig, M Agbaria… - Journal of Controlled …, 2023 - Elsevier
Despite tremendous global efforts since the beginning of the COVID-19 pandemic, still only
a limited number of prophylactic and therapeutic options are available. Although vaccination …

[HTML][HTML] Mucosal immunization with lipopeptides derived from conserved regions of SARS-CoV-2 antigens induce robust cellular and cross-variant humoral immune …

RS Patel, B Agrawal - Frontiers in Immunology, 2023 - frontiersin.org
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the causative agent of
COVID-19, has infected> 600 million people in the ongoing global pandemic. Several …

Role of different types of RNA molecules in the severity prediction of SARS-CoV-2 patients

P Jeyananthan - Pathology-Research and Practice, 2023 - Elsevier
SARS-CoV-2 pandemic is the current threat of the world with enormous number of
deceases. As most of the countries have constraints on resources, particularly for intensive …

[HTML][HTML] An Update on Toll-like Receptor 2, Its Function and Dimerization in Pro-and Anti-Inflammatory Processes

K Colleselli, A Stierschneider, C Wiesner - International Journal of …, 2023 - mdpi.com
While a certain level of inflammation is critical for humans to survive infection and injury, a
prolonged inflammatory response can have fatal consequences. Pattern recognition Toll-like …

[HTML][HTML] Biomimetic virus-like particles with magnetic core. From bioactivity to an immunodiagnostic tool

AA Mieloch, AM Mleczko, A Samelak-Czajka… - Chemical Engineering …, 2024 - Elsevier
In this study, biomimetic virus-like particles (VLPs) composed of superparamagnetic iron
oxide nanoparticles (SPIONs) and receptor binding domain (RBD) of the SARS-CoV-2 virus …

[HTML][HTML] Distinct Effects of Respiratory Viral Infection Models on miR-149-5p, IL-6 and p63 Expression in BEAS-2B and A549 Epithelial Cells

N Shahdab, C Ward, PM Hansbro, S Cummings… - Cells, 2024 - mdpi.com
Respiratory viruses cause airway inflammation, resulting in epithelial injury and repair.
miRNAs, including miR-149-5p, regulate different pathological conditions. We aimed to …